Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
[HTML][HTML] Cysteine metabolic circuitries: druggable targets in cancer
VDB Bonifácio, SA Pereira, J Serpa… - British journal of cancer, 2021 - nature.com
To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
Zwitterion‐Based hydrogen sulfide nanomotors induce multiple acidosis in tumor cells by destroying tumor metabolic symbiosis
M Wan, Z Liu, T Li, H Chen, Q Wang… - Angewandte …, 2021 - Wiley Online Library
Destruction of tumor metabolism symbiosis is an attractive cancer treatment method which
targets tumor cells with little harm to normal cells. Yet, a single intervention strategy and poor …
targets tumor cells with little harm to normal cells. Yet, a single intervention strategy and poor …
Hydrogen sulfide biology and its role in cancer
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …
Hydrogen sulfide, an endogenous stimulator of mitochondrial function in cancer cells
C Szabo - Cells, 2021 - mdpi.com
Hydrogen sulfide (H2S) has a long history as toxic gas and environmental hazard; inhibition
of cytochrome c oxidase (mitochondrial Complex IV) is viewed as a primary mode of its …
of cytochrome c oxidase (mitochondrial Complex IV) is viewed as a primary mode of its …
Intracellular bottom‐up synthesis of ultrasmall CuS nanodots in cancer cells for simultaneous photothermal therapy and COX‐2 inactivation
L Feng, S Wu, Y Wu - Advanced Functional Materials, 2021 - Wiley Online Library
The clinical application of photothermal therapy (PTT) is limited by the accuracy of thermal
damage and the risk of tumor metastasis and relapse induced by hyperthermia‐related …
damage and the risk of tumor metastasis and relapse induced by hyperthermia‐related …
Co-assembled Nanocarriers of De Novo Thiol-Activated Hydrogen Sulfide Donors with an RGDFF Pentapeptide for Targeted Therapy of Non-Small-Cell Lung Cancer
H Chen, X Guan, Q Liu, L Yang, J Guo… - … Applied Materials & …, 2022 - ACS Publications
Hydrogen sulfide releasing agents (or H2S donors) have been recognized gasotransmitters
with potent cytoprotective and anticancer properties. However, the clinical application of …
with potent cytoprotective and anticancer properties. However, the clinical application of …
The NRF2/KEAP1 axis in the regulation of tumor metabolism: mechanisms and therapeutic perspectives
The NRF2/KEAP1 pathway is a fundamental signaling cascade that controls multiple
cytoprotective responses through the induction of a complex transcriptional program that …
cytoprotective responses through the induction of a complex transcriptional program that …
[HTML][HTML] Hydrogen sulfide and its donors: Novel antitumor and antimetastatic therapies for triple-negative breast cancer
H Li, F Xu, G Gao, X Gao, B Wu, C Zheng, P Wang, Z Li… - Redox biology, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is considered as a novel second-messenger molecule associated
with the modulation of various physiological and pathological processes. In the field of …
with the modulation of various physiological and pathological processes. In the field of …
Roles of hydrogen sulfide donors in common kidney diseases
Hydrogen sulfide (H2S) plays a key role in the regulation of physiological processes in
mammals. The decline in H2S level has been reported in numerous renal disorders. In …
mammals. The decline in H2S level has been reported in numerous renal disorders. In …