Butyrate and the intestinal epithelium: modulation of proliferation and inflammation in homeostasis and disease

PS Salvi, RA Cowles - Cells, 2021 - mdpi.com
The microbial metabolite butyrate serves as a link between the intestinal microbiome and
epithelium. The monocarboxylate transporters MCT1 and SMCT1 are the predominant …

Recent advances in understanding the structure and function of the human microbiome

WK Mousa, F Chehadeh, S Husband - Frontiers in Microbiology, 2022 - frontiersin.org
Trillions of microbes live within our bodies in a deep symbiotic relationship. Microbial
populations vary across body sites, driven by differences in the environment, immunological …

Spherical mesoporous Fe-NC single-atom nanozyme for photothermal and catalytic synergistic antibacterial therapy

Y Feng, J Qin, Y Zhou, Q Yue, J Wei - Journal of Colloid and Interface …, 2022 - Elsevier
Nanozyme has been regarded as an efficient antibiotic to kill bacteria using the reactive
oxygen species (ROS) generated by Fenton-like reaction. However, its activity is still …

Alcohol, the gut microbiome, and liver disease

MH Jew, CL Hsu - Journal of Gastroenterology and Hepatology, 2023 - Wiley Online Library
The microorganisms inhabiting our gastrointestinal tract are critical for human health.
Chronic heavy alcohol use can modulate the composition and function of the gut microbiota …

The gut microbiome and substance use disorder

JT Russell, Y Zhou, GM Weinstock… - Frontiers in …, 2021 - frontiersin.org
Substance use disorders (SUDs) remain a significant public health challenge, affecting tens
of millions of individuals worldwide each year. Often comorbid with other psychiatric …

The critical role of short-chain fatty acids in health and disease: A subtle focus on cardiovascular disease-NLRP3 inflammasome-angiogenesis axis

J Yao, Y Chen, M Xu - Clinical Immunology, 2022 - Elsevier
Short-chain fatty acids (SCFAs), metabolites of intestinal microorganisms, have been linked
to the occurrence and development of a variety of disorders, including cardiovascular …

Metal–organic framework (MOF)-based single-atom iron catalysts for NIR-II enhanced catalytic-photothermal synergistic antibacterial therapy

C Ying, X Zhu, S Xiang, M Wang… - ACS Applied Nano …, 2023 - ACS Publications
Single-atom catalysts based on carbon-based materials have a high catalytic activity and
excellent photothermal performance. In this article, iron single-atom catalysts loaded on C …

[HTML][HTML] Metformin modulates microbiota-derived inosine and ameliorates methamphetamine-induced anxiety and depression-like withdrawal symptoms in mice

J Yang, Z Zhang, Z Xie, L Bai, P Xiong, F Chen… - Biomedicine & …, 2022 - Elsevier
Background Metformin exhibits therapeutic potential in behavioural deficits induced by
methamphetamine (METH) in rats. Emerging studies suggest gut microbiota may impact …

Substance use, microbiome and psychiatric disorders

ET Chivero, S Sil, M Kumar, S Buch - Pharmacology Biochemistry and …, 2022 - Elsevier
Accumulating evidence from several studies has shown association between substance
use, dysregulation of the microbiome and psychiatric disorders such as depression, anxiety …

Cocaine hydrochloride, cocaine methiodide and methylenedioxypyrovalerone (MDPV) cause distinct alterations in the structure and composition of the gut microbiota

M Angoa-Pérez, B Zagorac, DM Francescutti… - Scientific Reports, 2023 - nature.com
Cocaine is a highly addictive psychostimulant drug of abuse that constitutes an ongoing
public health threat. Emerging research is revealing that numerous peripheral effects of this …