This review discusses how lipophagy and cytosolic lipolysis degrade cellular lipids, as well
as how these pathway ys communicate, how they affect lipid metabolism and energy …

Background Cardiovascular disease continues to be the leading cause of death globally.
Clinical practice guidelines aimed at improving disease management and positively …

Objectives To assess the effects of whole-body vibration training (WBVT) on body
composition, metabolic and cardiovascular risk variables, and lower limb strength in …

Background: The monogenic defect in familial hypercholesterolemia (FH) is detected in∼
40% of cases. The majority of mutation-negative patients have a polygenic cause of high …

Background Clinically diagnosed familial hypercholesterolemia (FH) may require a genetic
test (GT) to confirm diagnosis. GT availability/accessibility is resource-dependent and …

Abstract Purpose of Review Genetic testing has proven utility in identifying and diagnosing
individuals with FH. Here we outline the current landscape of genetic testing for FH …

Background: Patient-reported outcomes (PROs) and PRO measures (PROMs) are real-
world evidence that can help capture patient experiences and perspectives regarding a …

家族性高胆固醇血症(FH) 是一种常见的常染色体显性或隐性遗传代谢病, 常用的临床诊断标准
主要根据患者的低密度脂蛋白胆固醇(LDL-C) 水平和健康调查信息进行诊断, 其确诊率十分有限 …

Patient-reported outcomes (PROs) and PRO measures (PROMs) are often used to help
clinicians and researchers understand patients' personal concerns, feelings, experiences …

We report a single-point variant of low-density lipoprotein receptor (LDLR) in a Chinese
proband with a clinical diagnosis of familial hypercholesterolemia (FH) with a …