[HTML][HTML] Targeting PI3K/AKT/mTOR signaling pathway in pancreatic cancer: from molecular to clinical aspects

S Stanciu, F Ionita-Radu, C Stefani, D Miricescu… - International journal of …, 2022 - mdpi.com
Although pancreatic cancer (PC) was considered in the past an orphan cancer type due to
its low incidence, it may become in the future one of the leading causes of cancer death …

Clinical aspects of multiple endocrine neoplasia type 1

A Al-Salameh, G Cadiot, A Calender… - Nature Reviews …, 2021 - nature.com
Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome characterized by the co-
occurrence of primary hyperparathyroidism, duodenopancreatic neuroendocrine tumours …

The North American Neuroendocrine Tumor Society consensus paper on the surgical management of pancreatic neuroendocrine tumors

JR Howe, NB Merchant, C Conrad, XM Keutgen… - Pancreas, 2020 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the surgical management of pancreatic neuroendocrine tumors …

ENETS consensus guidelines update for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine …

M Falconi, B Eriksson, G Kaltsas, DK Bartsch… - …, 2016 - karger.com
Only advances that occurred from 2011 to 2014 that either strengthen the previous 2011
guidelines [1, 2] or lead to changes or additional guidelines are reviewed here. Advances …

[HTML][HTML] Multiple endocrine neoplasia type 1 (MEN1): an update and the significance of early genetic and clinical diagnosis

CDC Kamilaris, CA Stratakis - Frontiers in endocrinology, 2019 - frontiersin.org
Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in
an autosomal dominant manner and characterized by a predisposition to a multitude of …

Everolimus for advanced pancreatic neuroendocrine tumors

JC Yao, MH Shah, T Ito, CL Bohas… - … England Journal of …, 2011 - Mass Medical Soc
Background Everolimus, an oral inhibitor of mammalian target of rapamycin (mTOR), has
shown antitumor activity in patients with advanced pancreatic neuroendocrine tumors, in two …

Multiple endocrine neoplasia type 1 and the pancreas: diagnosis and treatment of functioning and non-functioning pancreatic and duodenal neuroendocrine …

B Niederle, A Selberherr, DK Bartsch, ML Brandi… - …, 2021 - karger.com
The better understanding of the biological behavior of multiple endocrine neoplasia type 1
(MEN1) organ manifestations and the increase in clinical experience warrant a revision of …

ENETS consensus guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes

RT Jensen, G Cadiot, ML Brandi, WW De Herder… - …, 2012 - karger.com
Gastrinomas are neuroendocrine neoplasms, usually located in the duodenum or pancreas,
that secrete gastrin and cause a clinical syndrome known as Zollinger-Ellison syndrome …

Recent updates on grading and classification of neuroendocrine tumors

JY Kim, SM Hong, JY Ro - Annals of diagnostic pathology, 2017 - Elsevier
Neuroendocrine tumors (NETs) are originating from neuroendocrine cells in diffuse
endocrine systems. NETs are diagnosed by characteristic histologic features and …

Pancreatic neuroendocrine neoplasms: 2020 update on pathologic and imaging findings and classification

L Khanna, SR Prasad, A Sunnapwar, S Kondapaneni… - Radiographics, 2020 - pubs.rsna.org
Pancreatic neuroendocrine neoplasms (panNENs) are heterogeneous neoplasms with
neuroendocrine differentiation that show characteristic clinical, histomorphologic, and …