[HTML][HTML] Chromatin remodeling BAF (SWI/SNF) complexes in neural development and disorders
G Sokpor, Y Xie, J Rosenbusch, T Tuoc - Frontiers in molecular …, 2017 - frontiersin.org
The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes
are crucial in regulating gene expression by controlling chromatin dynamics. Over the last …
are crucial in regulating gene expression by controlling chromatin dynamics. Over the last …
Homology, neocortex, and the evolution of developmental mechanisms
SD Briscoe, CW Ragsdale - Science, 2018 - science.org
The six-layered neocortex of the mammalian pallium has no clear homolog in birds or non-
avian reptiles. Recent research indicates that although these extant amniotes possess a …
avian reptiles. Recent research indicates that although these extant amniotes possess a …
Vascular contributions to 16p11. 2 deletion autism syndrome modeled in mice
While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled,
vascular contributions to ASD remain elusive. Here, we investigated postnatal …
vascular contributions to ASD remain elusive. Here, we investigated postnatal …
[HTML][HTML] Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity
Identities of distinct neuron subtypes are specified during embryonic development, then
maintained during post-natal maturation. In cerebral cortex, mechanisms controlling early …
maintained during post-natal maturation. In cerebral cortex, mechanisms controlling early …
Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex
DJ Di Bella, N Domínguez-Iturza, JR Brown, P Arlotta - Neuron, 2024 - cell.com
Since the beautiful images of Santiago Ramón y Cajal provided a first glimpse into the
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …
[HTML][HTML] Transcriptomic cell type structures in vivo neuronal activity across multiple timescales
Cell type is hypothesized to be a key determinant of a neuron's role within a circuit. Here, we
examine whether a neuron's transcriptomic type influences the timing of its activity. We …
examine whether a neuron's transcriptomic type influences the timing of its activity. We …
[HTML][HTML] Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting
V Sahni, Y Itoh, SJ Shnider, JD Macklis - Cell reports, 2021 - cell.com
The cerebral cortex executes highly skilled movement, necessitating that it connects
accurately with specific brainstem and spinal motor circuitry. Corticospinal neurons (CSN) …
accurately with specific brainstem and spinal motor circuitry. Corticospinal neurons (CSN) …
[HTML][HTML] Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes
Investigation of translation in rare cell types or subcellular contexts is challenging due to
large input requirements for standard approaches. Here, we present" nanoRibo-seq" an …
large input requirements for standard approaches. Here, we present" nanoRibo-seq" an …
[HTML][HTML] Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting
For precise motor control, distinct subpopulations of corticospinal neurons (CSN) must
extend axons to distinct spinal segments, from proximal targets in the brainstem and cervical …
extend axons to distinct spinal segments, from proximal targets in the brainstem and cervical …
[HTML][HTML] Bcl11 transcription factors regulate cortical development and function
R Simon, C Wiegreffe, S Britsch - Frontiers in molecular neuroscience, 2020 - frontiersin.org
Transcription factors regulate multiple processes during brain development and in the adult
brain, from brain patterning to differentiation and maturation of highly specialized neurons as …
brain, from brain patterning to differentiation and maturation of highly specialized neurons as …