[HTML][HTML] Chromatin remodeling BAF (SWI/SNF) complexes in neural development and disorders

G Sokpor, Y Xie, J Rosenbusch, T Tuoc - Frontiers in molecular …, 2017 - frontiersin.org
The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes
are crucial in regulating gene expression by controlling chromatin dynamics. Over the last …

Homology, neocortex, and the evolution of developmental mechanisms

SD Briscoe, CW Ragsdale - Science, 2018 - science.org
The six-layered neocortex of the mammalian pallium has no clear homolog in birds or non-
avian reptiles. Recent research indicates that although these extant amniotes possess a …

Vascular contributions to 16p11. 2 deletion autism syndrome modeled in mice

J Ouellette, X Toussay, CH Comin, LF Costa… - Nature …, 2020 - nature.com
While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled,
vascular contributions to ASD remain elusive. Here, we investigated postnatal …

[HTML][HTML] Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity

MJ Galazo, DA Sweetser, JD Macklis - Cell reports, 2023 - cell.com
Identities of distinct neuron subtypes are specified during embryonic development, then
maintained during post-natal maturation. In cerebral cortex, mechanisms controlling early …

Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex

DJ Di Bella, N Domínguez-Iturza, JR Brown, P Arlotta - Neuron, 2024 - cell.com
Since the beautiful images of Santiago Ramón y Cajal provided a first glimpse into the
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …

[HTML][HTML] Transcriptomic cell type structures in vivo neuronal activity across multiple timescales

A Schneider, M Azabou, L McDougall-Vigier, DF Parks… - Cell reports, 2023 - cell.com
Cell type is hypothesized to be a key determinant of a neuron's role within a circuit. Here, we
examine whether a neuron's transcriptomic type influences the timing of its activity. We …

[HTML][HTML] Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting

V Sahni, Y Itoh, SJ Shnider, JD Macklis - Cell reports, 2021 - cell.com
The cerebral cortex executes highly skilled movement, necessitating that it connects
accurately with specific brainstem and spinal motor circuitry. Corticospinal neurons (CSN) …

[HTML][HTML] Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes

JE Froberg, O Durak, JD Macklis - Cell reports, 2023 - cell.com
Investigation of translation in rare cell types or subcellular contexts is challenging due to
large input requirements for standard approaches. Here, we present" nanoRibo-seq" an …

[HTML][HTML] Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting

V Sahni, SJ Shnider, D Jabaudon, JHT Song, Y Itoh… - Cell Reports, 2021 - cell.com
For precise motor control, distinct subpopulations of corticospinal neurons (CSN) must
extend axons to distinct spinal segments, from proximal targets in the brainstem and cervical …

[HTML][HTML] Bcl11 transcription factors regulate cortical development and function

R Simon, C Wiegreffe, S Britsch - Frontiers in molecular neuroscience, 2020 - frontiersin.org
Transcription factors regulate multiple processes during brain development and in the adult
brain, from brain patterning to differentiation and maturation of highly specialized neurons as …