Abuse and misuse of pregabalin and gabapentin: a systematic review update

KE Evoy, S Sadrameli, J Contreras, JR Covvey… - Drugs, 2021 - Springer
Background A 2017 systematic review (SR) identified 59 studies examining gabapentinoid
(pregabalin and gabapentin) misuse/abuse. Evidence of gabapentinoid misuse/abuse has …

How addictive are gabapentin and pregabalin? A systematic review

U Bonnet, N Scherbaum - European neuropsychopharmacology, 2017 - Elsevier
In the last ten years, gabapentin and pregabalin have been becoming dispensed broadly
and sold on black markets, thereby, exposing millions to potential side-effects. Meanwhile …

The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder

VI Reus, LJ Fochtmann, O Bukstein… - American Journal of …, 2018 - Am Psychiatric Assoc
The goal of this guideline1 is to improve the quality of care and treatment outcomes for
patients with alcohol use disorder (AUD), as defined by DSM-5 (American Psychiatric …

Alpha2delta ligands, gabapentin, pregabalin and mirogabalin: a review of their clinical pharmacology and therapeutic use

EP Calandre, F Rico-Villademoros… - Expert review of …, 2016 - Taylor & Francis
Introduction: The first two alpha2delta ligands–gabapentin (GBP) and pregabalin (PGB)–
were initially synthesized as antiepileptics; however, they were later also found to be useful …

Risk to heroin users of polydrug use of pregabalin or gabapentin

A Lyndon, S Audrey, C Wells, ES Burnell, S Ingle… - …, 2017 - Wiley Online Library
Aim To examine the risk to heroin users of also using gabapentin or pregabalin
(gabapentoids). Design Multi‐disciplinary study: we (a) examined trends in drug‐related …

Gabapentinoids: pharmacokinetics, pharmacodynamics and considerations for clinical practice

M Chincholkar - British journal of pain, 2020 - journals.sagepub.com
The gabapentinoids are often recommended as first-line treatments for the management of
neuropathic pain. The differing pharmacodynamic and pharmacokinetic profiles can have …

Pharmacologic therapy for acute pain

O Amaechi, MMC Human, K Featherstone - American family physician, 2021 - aafp.org
Pharmacologic management of acute pain should be tailored for each patient, including a
review of treatment expectations and a plan for the time course of prescriptions …

Risk of neonatal drug withdrawal after intrauterine co-exposure to opioids and psychotropic medications: cohort study

KF Huybrechts, BT Bateman, RJ Desai… - bmj, 2017 - bmj.com
Objectives To assess the impact of in utero co-exposure to psychotropic medications and
opioids on the incidence and severity of neonatal drug withdrawal. Design Observational …

Albumin nanoscience: homing nanotechnology enabling targeted drug delivery and therapy

S Lamichhane, S Lee - Archives of pharmacal research, 2020 - Springer
Albumin is a biocompatible, non-immunogenic and versatile drug carrier system. It has been
widely used to extend the half-life, enhance stability, provide protection from degradation …

Gabapentinoid benefit and risk stratification: mechanisms over myth

H McAnally, U Bonnet, AD Kaye - Pain and therapy, 2020 - Springer
Introduction Recent years have seen a dramatic escalation of off-label prescribing for
gabapentin and pregabalin (gabapentinoids) owing in part to generic versions of each being …