Non-selective beta-blockers (NSBBs) are the mainstay of treatment for portal hypertension in
the setting of liver cirrhosis. Randomised controlled trials demonstrated their efficacy in …

Gastroesophageal varices are present at diagnosis in almost half of patients with cirrhosis,
and variceal hemorrhage continues to be a lethal complication of cirrhosis. This review …

The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

This Practice Guidance from the American Association for the Study of Liver Disease
(AASLD) intends to coalesce best practice recommendations for the identification of portal …

The natural history of cirrhosis can be divided into a preclinical phase and a subsequent
clinical phase. The preclinical phase is usually prolonged over several years; once clinical …

Portal HYPERTENSION is the hemodynamic dbnormahty associdted with the most severe
comphcations of cirrhosis, mcludmg ascltes, hepatlc encephalopathy and bleeding from …

Variceal bleeding is the last step in a chain of events initiated by an increase in portal
pressure, followed by the development and progressive dilation of varices until these finally …

Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

The management of portal hypertension should be based on an updated knowledge of its
natural history. Portal hypertension is an almost unavoidable complication of cirrhosis, and it …

Clin Mol Hepatol Volume_26 Number_2 April 2020 https://doi. org/10.3350/cmh. 2019.0010
n clinical practice. Therefore, these revised guidelines for the treatment of varices and HE …