Recent advances and therapeutic journey of Schiff base complexes with selected metals (Pt, Pd, Ag, Au) as potent anticancer agents: A review

S Khan, FA Alhumaydhi, MM Ibrahim… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Schiff bases and their transition metal complexes play an important role in the field of
medicine, in particular in the treatment of cancer. Since the discovery of the cisplatin …

Antitumor activity of tridentate pincer and related metal complexes

S Wu, Z Wu, Q Ge, X Zheng, Z Yang - Organic & Biomolecular …, 2021 - pubs.rsc.org
Pincer complexes featuring tunable tridentate ligand frameworks are one of the most actively
studied classes of metal-based complexes. Currently, growing attention is devoted to the …

[HTML][HTML] Novel pyrazolo [3, 4-d] pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action

Z Ruzi, K Bozorov, L Nie, J Zhao, HA Aisa - Biomedicine & …, 2022 - Elsevier
Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition,
and mechanisms of action - ScienceDirect Skip to main contentSkip to article Elsevier logo …

Hydrazylpyridine salicylaldehyde–copper (ii)–1, 10-phenanthroline complexes as potential anticancer agents: synthesis, characterization and anticancer evaluation

Y Chen, Z Ke, L Yuan, M Liang, S Zhang - Dalton Transactions, 2023 - pubs.rsc.org
We synthesized and analyzed nine unique copper (II) hydrazylpyridine salicylaldehyde and
1, 10-phenanthroline complexes,[Cu (L1a)(phen)](Cugdupt1),[Cu (L2a)(phen)]·(CH3CN) …

A new palladium (II) phosphino complex with ONS donor Schiff base ligand: Synthesis, characterization and catalytic activity towards Suzuki-Miyaura cross-coupling …

CK Manna, R Naskar, B Bera, A Das… - Journal of Molecular …, 2021 - Elsevier
New palladium (II) phosphino complex,[Pd (PPh 3)(L)](ClO 4)(1) with thioether containing
ONS donor Schiff base ligand (HL) is synthesized by the reaction of HL with sodium …

Pd (II) and Pt (II) trinuclear chelates with spermidine: selective anticancer activity towards TNBC-sensitive and-resistant to cisplatin

M Vojtek, CB Martins, R Ramos, SG Duarte, IM Ferreira… - Pharmaceutics, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer
and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such …

Inhibition of SREBP-mediated lipid biosynthesis and activation of multiple anticancer mechanisms by platinum complexes: Ascribe possibilities of new antitumor …

X Bai, A Ali, N Wang, Z Liu, Z Lv, Z Zhang… - European Journal of …, 2022 - Elsevier
Cancer is one of the most aggressive diseases with poor prognosis and survival rates.
Lipids biogenesis play key role in cancer progression, metastasis and tumor development …

Monofunctional dimetallic Ru (η6-arene) complexes inhibit NOTCH1 signaling pathway and synergistically enhance anticancer effect in combination with cisplatin or …

N Wang, A Ali, Z Liu, H Chi, Z Lv, X Zhao… - European Journal of …, 2023 - Elsevier
Abstract ONS donor ligands L1-L4 were utilized in the preparation of monofunctional
dimetallic Ru (η6-arene) complexes (C1–C4). These ONS donor ligand based novel …

Differences in stability, cytotoxicity, and mechanism of action of Ru (II) and Pt (II) complexes of a bidentate N, O donor ligand

M Maji, S Acharya, S Maji, K Purkait, A Gupta… - Inorganic …, 2020 - ACS Publications
We report [RuII (L)(η6-p-cym) Cl](1 and 2) and [PtII (L)(DMSO) Cl](3 and 4) complexes,
where L is a chelate imine ligand derived from chloroethylamine and salicylaldehyde (HL1) …

A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

K Al-Khayal, MA Vaali-Mohammed, M Elwatidy… - Bmc Cancer, 2020 - Springer
Background Colorectal cancer (CRC) is a heterogeneous tumor having various genetic
alterations. The current treatment options had limited impact on disease free survival due to …