[HTML][HTML] Nutrition, longevity and disease: From molecular mechanisms to interventions

VD Longo, RM Anderson - Cell, 2022 - cell.com
Diet as a whole, encompassing food composition, calorie intake, and the length and
frequency of fasting periods, affects the time span in which health and functional capacity …

The gut microbiome in Alzheimer's disease: what we know and what remains to be explored

S Chandra, SS Sisodia, RJ Vassar - Molecular neurodegeneration, 2023 - Springer
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …

Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

H Zhu, D Bi, Y Zhang, C Kong, J Du, X Wu… - Signal transduction and …, 2022 - nature.com
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

Effect of diet and dietary components on the composition of the gut microbiota

A Beam, E Clinger, L Hao - Nutrients, 2021 - mdpi.com
Diet and dietary components have profound effects on the composition of the gut microbiota
and are among the most important contributors to the alteration in bacterial flora. This review …

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

SC Cunnane, E Trushina, C Morland… - Nature reviews Drug …, 2020 - nature.com
The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

The potential role of gut microbiota in Alzheimer's disease: from diagnosis to treatment

A Varesi, E Pierella, M Romeo, GB Piccini, C Alfano… - Nutrients, 2022 - mdpi.com
Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …

Gut microbiota Turicibacter strains differentially modify bile acids and host lipids

JB Lynch, EL Gonzalez, K Choy, KF Faull… - Nature …, 2023 - nature.com
Bacteria from the Turicibacter genus are prominent members of the mammalian gut
microbiota and correlate with alterations in dietary fat and body weight, but the specific …

Lipids and Alzheimer's disease

YC Kao, PC Ho, YK Tu, IM Jou, KJ Tsai - International journal of molecular …, 2020 - mdpi.com
Lipids, as the basic component of cell membranes, play an important role in human health
as well as brain function. The brain is highly enriched in lipids, and disruption of lipid …

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild …

R Nagpal, BJ Neth, S Wang, S Craft, H Yadav - EBioMedicine, 2019 - thelancet.com
Background Alzheimer's disease (AD) prevalence is increasing, but its etiology remains
elusive. Gut microbes can contribute to AD pathology and may help identifying novel …

[HTML][HTML] Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases

C Gubert, G Kong, T Renoir, AJ Hannan - Neurobiology of disease, 2020 - Elsevier
The last decade has witnessed an exponentially growing interest in gut microbiota and the
gut-brain axis in health and disease. Accumulating evidence from preclinical and clinical …