The recent advance in technology for mass spectrometry-based targeted protein
quantification has opened new avenues for a broad range of proteomic applications in …

Biotechnology increasingly delivers highly promising protein-based biopharmaceutical
candidates to the drug development funnel. For successful biopharmaceutical drug …

The development of mass spectrometry (MS)-based methodologies for high-throughput
protein identification has generated a concomitant need for protein quantification. Numerous …

During the past decade, tandem mass spectrometry hyphenated to liquid chromatography
separation systems (HPLC–MS/MS) has developed to an important technology in clinical …

The accurate quantitation of proteins and peptides in complex biological systems is one of
the most challenging areas of proteomics. Mass spectrometry‐based approaches have …

Ligand binding assays (LBAs) are widely used for therapeutic monoclonal antibody (mAb)
quantification in biological samples. Major limitations are long method development times …

A rapid acetonitrile (ACN)‐based extraction method has been developed that reproducibly
depletes high abundance and high molecular weight proteins from serum prior to mass …

The LC-triple quadrupole mass spectrometer (LC–MS/MS) is an increasingly common tool in
the clinical laboratory. Established applications include routine assays for detecting inborn …

Clinical laboratory medicine has seen the introduction and evolution of liquid
chromatography tandem mass spectrometry in routine clinical laboratories over the last 10 …

With the growing interest for peptides and proteins in different kinds of fields, eg pharmacy,
clinical diagnostics or food industry, the quantification of these compounds is becoming …