Ovarian cancer (OC) represents a collection of rare but lethal gynecologic cancers where
the difficulty of early detection due to an often-subtle range of abdominal symptoms …

Progesterone (PRG) is a key cyclical reproductive hormone that has a significant impact on
female organs in vertebrates. It is mainly produced by the corpus luteum of the ovaries, but …

Sigma receptors are non-opiate/non-phencyclidine receptors that bind progesterone and/or
heme and also several unrelated xenobiotics/chemicals. They reside in the plasma …

Simple Summary PGRMC1 is a multifunctional protein regulating multiple aspects of cell
proliferation, including cell viability, apoptosis, entry into the cell cycle, and the subsequent …

The title usage of Latin Quo vadis 'where are you going'extends the question Unde venisti
from where 'did you come?'posed in the accompanying paper and extends consideration of …

Several receptors for nongenomically initiated actions of progesterone (P4) exist, namely
membrane-associated P4 receptors (MAPRs), membrane progestin receptors (mPRs) …

Acquisition of developmental competence is a complex process in which many cell types
cooperate to support oocyte maturation, fertilisation, and preimplantation embryonic …

Progesterone receptor membrane component 1 (PGRMC1) is one of few proteins that have
been recently described as direct modulators of the activity of human cytochrome P450 …

Uterine leiomyomas (ULs) are the most common benign smooth muscle cell steroid-
dependent tumors that occur in women of reproductive age. Progesterone (P4) is a major …

Abstract Progesterone Receptor Membrane Component 1 (PGRMC1) is a candidate
oncogene with a prominent involvement in the pathogenesis of diverse cancers (ovarian …