Fungal diseases kill more than 1.5 million and affect over a billion people. However, they are
still a neglected topic by public health authorities even though most deaths from fungal …

Although fungal infections contribute substantially to human morbidity and mortality, the
impact of these diseases on human health is not widely appreciated. Moreover, despite the …

Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Invasive aspergillosis (IA) in haematology/oncology patients presents as primary infection or
breakthrough infection, which can become refractory to antifungal treatment and has a high …

Rationale: The clinical relevance of Aspergillus-positive endotracheal aspirates in critically
ill patients is difficult to assess. Objectives: We externally validate a clinical algorithm to …

Understanding the tissue penetration of systemically administered antifungal agents is
critical for a proper appreciation of their antifungal efficacy in animals and humans. Both the …

Introduction Invasive aspergillosis (IA) is a fungal infection that particularly affects
immunocompromised hosts. Recently, several studies have indicated a high incidence of IA …

Recent investigations have yielded both profound insights into the mechanisms required by
pathogenic fungi for virulence within the human host, as well as novel potential targets for …

Chronic pulmonary aspergillosis (CPA) is a condition caused by the ubiquitous fungus
Aspergillus fumigatus in non-immunocompromised individuals. Numerous underlying …

Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal
drug resistance, novel strategies are urgently needed to combat life-threatening fungal …