Frontiers in the treatment of glioblastoma: Past, present and emerging
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …
research over the last several decades, the survival rates for GBM have not improved and …
[HTML][HTML] Glioblastoma: overview of disease and treatment
ME Davis - Clinical journal of oncology nursing, 2016 - ncbi.nlm.nih.gov
Background Glioblastoma (GBM) is the most common and aggressive malignant brain tumor
in adults. Current treatment options at diagnosis are multimodal and include surgical …
in adults. Current treatment options at diagnosis are multimodal and include surgical …
Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma
G Lu, X Wang, F Li, S Wang, J Zhao, J Wang… - Nature …, 2022 - nature.com
Glioblastoma multiforme (GBM) is an aggressive brain cancer with a poor prognosis and few
treatment options. Here, building on the observation of elevated lactate (LA) in resected …
treatment options. Here, building on the observation of elevated lactate (LA) in resected …
Exosomal noncoding RNAs in Glioma: biological functions and potential clinical applications
J Cheng, J Meng, L Zhu, Y Peng - Molecular cancer, 2020 - Springer
Gliomas are complex and heterogeneous brain tumors with poor prognosis. Glioma cells
can communicate with their surroundings to create a tumor-permissive microenvironment …
can communicate with their surroundings to create a tumor-permissive microenvironment …
Mechanisms of resistance and current treatment options for glioblastoma multiforme (GBM)
Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …
[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain
LL Israel, A Galstyan, E Holler, JY Ljubimova - Journal of Controlled …, 2020 - Elsevier
Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …
studied extensively during the past 20 years for numerous biomedical applications. The …
Current and future strategies for treatment of glioma
NAO Bush, SM Chang, MS Berger - Neurosurgical review, 2017 - Springer
Gliomas are one of the most common types of primary brain tumors and have remained
particularly challenging to treat. This review illustrates a multidisciplinary approach to the …
particularly challenging to treat. This review illustrates a multidisciplinary approach to the …
Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy
JV Gregory, P Kadiyala, R Doherty, M Cadena… - Nature …, 2020 - nature.com
Glioblastoma (GBM), the most aggressive form of brain cancer, has witnessed very little
clinical progress over the last decades, in part, due to the absence of effective drug delivery …
clinical progress over the last decades, in part, due to the absence of effective drug delivery …
Diagnostic and therapeutic biomarkers in glioblastoma: current status and future perspectives
W Szopa, TA Burley, G Kramer-Marek… - BioMed research …, 2017 - Wiley Online Library
Glioblastoma (GBM) is a primary neuroepithelial tumor of the central nervous system,
characterized by an extremely aggressive clinical phenotype. Patients with GBM have a …
characterized by an extremely aggressive clinical phenotype. Patients with GBM have a …
ROS‐responsive polymeric siRNA nanomedicine stabilized by triple interactions for the robust glioblastoma combinational RNAi therapy
Small interfering RNA (siRNA) holds inherent advantages and great potential for treating
refractory diseases. However, lack of suitable siRNA delivery systems that demonstrate …
refractory diseases. However, lack of suitable siRNA delivery systems that demonstrate …