Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including cancer, and is increasingly recognized as a growing cause of preventable cancer …

Abstract Interleukin-6 (IL-6) is a multifunctional cytokine with well-defined pro-and anti-
inflammatory properties. Although only small amounts in the picogram range can be …

The tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) involves a
significant accumulation of fibroblasts as part of the host response to cancer. Using single …

Pancreatitis is a common disorder with significant morbidity and mortality, yet little is known
about its pathogenesis, and there is no specific or effective treatment. Its development …

Pancreatitis is inflammation of pancreas and caused by a number of factors including
pancreatic duct obstruction, alcoholism, and mutation in the cationic trypsinogen gene …

Acute pancreatitis (AP) is an acute inflammation of the pancreas associated with high
morbidity and mortality. Endocrine pancreatic insufficiency secondary to AP has drawn …

Curcumin is apolyphenolic cominflammatory effects of curcumin. Moreover, curcumin can be
considered as potential therapy against IL-6 involvepound found in the dietary spice …

Pancreatic cancer has one of the poorest prognoses of all malignancies, with little
improvement in clinical outcome over the past 40 years. Pancreatic ductal adenocarcinoma …

Gastrointestinal cancer (GI) is a major health problem. Patients with gastric, pancreatic,
colorectal, bile duct and gall bladder cancer often have advanced disease at the time of …

Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most chemoresistant
cancers, and current therapies targeting cancer-associated molecular pathways have not …