Introduction It is currently admitted that adverse drug reactions (ADRs) account for a great
burden of disease. Of particular concern are ADR-induced hospital admissions, particularly …

When questioned, about 10% of the parents report suspected hypersensitivity to at least one
drug in their children. However, only a few of these reactions can be confirmed as allergic …

Background Adverse drug reactions (ADRs) represent a major cause of iatrogenic morbidity
and mortality in patient care. While a substantial body of work has been undertaken to …

Most immune-mediated adverse drug reactions (IM-ADRs) involve the skin, and many have
additional systemic features. Severe cutaneous adverse drug reactions (SCARs) are an …

OBJECTIVES The safe use of medications in pediatric patients requires practitioners to
consider the unique pharmacokinetics and pharmacodynamics of drugs prescribed in this …

The overlabeling of pediatric antibiotic allergy represents a huge burden in society. Given
that up to 10% of the US population is labeled as penicillin allergic, it can be estimated that …

One approach to experimental science involves creating hypotheses, then testing them by
varying one or more independent variables, and assessing the effects of this variation on the …

Background: Worldwide, in the absence of standard pediatric prescribing information,
clinicians often use medicines in children in a dosage form or for an indication that has not …

Background Patients reporting drug allergy are treated with second-line therapies, with
possible negative clinical and health consequences. Objective To assess the prevalence of …

Featured Application A deeper insight into oral lesions potentially detectable in pediatric
SARS-CoV-2 positive subjects and following COVID-19 vaccination may enhance clinicians' …