Muenke syndrome (MS) is an autosomal dominant coronal craniosynostosis syndrome with
variable extracranial anomalies. We studied 56 unrelated patients with non‐syndromic uni …

Animal models are useful to study the molecular, cellular, and morphogenetic mechanisms
underlying normal and pathological development. Cell‐based study models have emerged …

BACKGROUND Endometriosis is a polygenic disease with a complex and multifactorial
aetiology that affects 8–10% of women of reproductive age. Epidemiological data support a …

Pathological cardiac hypertrophy and cardiac fibrosis are remodeling events that result in
mechanical stiffness and pathophysiological changes in the myocardium. Both humans and …

Two mutations in FGFR3, G380R and G375C are known to cause achondroplasia, the most
common form of human dwarfism. The G380R mutation accounts for 98% of the …

Regulation of spermatogonial maintenance in the human testis is currently not well
understood. One pathway suggested to be involved is activated by fibroblast growth factor …

The present invention relates to a method of promoting hair growth comprising administering
a fibroblast growth factor receptor 4 (FGFR4) extracellular domain (ECD), including native …

The chemokine stromal cell–derived factor-1 (SDF-1) is constitutively expressed by bone
marrow stromal cells and plays key roles in hematopoiesis. Fibroblast growth factor 2 …

The A391E mutation in fibroblast growth factor receptor 3 (FGFR3) is the genetic cause for
Crouzon syndrome with Acanthosis Nigricans. Here we investigate the effect of this mutation …

Background Fibroblast growth factor receptor 1 (FGFR1) mRNA can be alternatively spliced
to generate isoforms containing (FGFR1α) or lacking (FGFR1β) the first immunoglobulin‐like …