Forkhead box class O family member proteins (FoxOs) are evolutionarily conserved
transcription factors for their highly conserved DNA-binding domain. In mammalian species …

Bone marrow mesenchymal stem cells (MSCs) are multipotent stem cells with the ability to
differentiate into bone-producing cells, which is essential for bone formation. Magnesium …

Introduction: One of the key factors that may influence the therapeutic potential of
mesenchymal stem/stromal cells (MSCs) is their metabolism. The switch between …

Arteriosclerosis causes significant morbidity and mortality worldwide. Central to this process
is the development of subclinical non-atherosclerotic intimal lesions before the appearance …

Osteogenic differentiation of multipotent mesenchymal stem cells (MSCs) plays a crucial role
in bone remodeling. Numerous studies have described the deleterious effect of iron …

What effects might arise from early life exposures to high iron? This review considers the
specific effects of high iron on the brain, stem cells, and the process of erythropoiesis and …

Although the complex mechanism by which skeletal tissue heals has been well described,
the role of reactive oxygen species (ROS) in skeletal tissue regeneration is less understood …

Iron overload is common in patients with diseases such as hemoglobinopathies, hereditary
hemochromatosis or elderly men and postmenopausal women. This disorder is frequently …

Melatonin has the ability to intervene in the initiation, progression and metastasis of some
experimental cancers. A large variety of potential mechanisms have been advanced to …

Cells of unicellular and multicellular eukaryotes can respond to certain environmental cues
by arresting the cell cycle and entering a reversible state of quiescence. Quiescent cells do …