Objective To investigate the effect and mechanism of Glucocorticoids (GCs) induced
oxidative stress and apoptosis on necrosis of the femoral head in patients and rats. Methods …

Introduction: One of the key factors that may influence the therapeutic potential of
mesenchymal stem/stromal cells (MSCs) is their metabolism. The switch between …

Bone remodeling is a continuous physiological process that requires constant generation of
new osteoblasts from mesenchymal stem cells (MSCs). Differentiation of MSCs to osteoblast …

Focal radiotherapy is frequently associated with skeletal damage within the radiation field.
Our previous in vitro study showed that activation of Wnt/β‐catenin pathway can overcome …

Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …

Mesenchymal stem cells (MSCs) are multipotent precursor cells originating from several
adult connective tissues. MSCs possess the ability to self-renew and differentiate into …

Osseous tissue repair has advanced due to the introduction of tissue engineering. The key
elements required while engineering new tissues involve scaffolds, cells, and bioactive …

Periodontal ligament stem cell (PDLSC)-based tissue engineering is an important method
for regenerating lost bone in periodontitis. Maintaining or enhancing the osteogenic …

Human adipose tissue is a great source of adult mesenchymal stem cells (MSC s) which are
recognized from their ability to self‐renew and differentiation into multiple lineages. MSC s …

Aging is associated with decreased bone mass and accumulation of bone marrow
adipocytes. Both bone forming osteoblastic cells and bone marrow adipocytes are derived …