Co-encapsulation of tamoxifen and quercetin in polymeric nanoparticles: implications on oral bioavailability, antitumor efficacy, and drug-induced toxicity

AK Jain, K Thanki, S Jain - Molecular pharmaceutics, 2013 - ACS Publications
The present investigation reports the preparation, optimization, and characterization of orally
administrable PLGA-NPs co-encapsulated with tamoxifen (Tmx) and quercetin (QT). The …

Therapeutic effect of quercetin in collagen-induced arthritis

N Haleagrahara, S Miranda-Hernandez… - Biomedicine & …, 2017 - Elsevier
Quercetin, a bioactive flavonoid with anti-inflammatory, immunosuppressive, and protective
properties, is a potential agent for the treatment of rheumatoid arthritis (RA). Collagen …

Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer—part 2

SM Sagar, D Yance, RK Wong - Current Oncology, 2006 - mdpi.com
The herbalist has access to hundreds of years of observational data on the anticancer
activity of many herbs. Laboratory studies are expanding the clinical knowledge that is …

Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities

CJ Weng, GC Yen - Cancer and Metastasis Reviews, 2012 - Springer
Cancer metastasis refers to the spread of cancer cells from the primary neoplasm to distant
sites, where secondary tumors are formed, and is the major cause of death from cancer …

Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells

Y Ling, Y Yang, N Lu, Q You, S Wang, Y Gao… - Biochemical and …, 2007 - Elsevier
Endostar, a novel recombinant human endostatin expressed and purified in Escherichia coli
with an additional nine-amino acid sequence and forming another his-tag structure, was …

Phenolic compounds as nutraceuticals or functional food ingredients

C Caleja, A Ribeiro… - Current …, 2017 - ingentaconnect.com
Background: Nowadays, the functional foods represent one the most promising, interesting
and innovative areas in the food industry. Various components are being added to foods in …

Antiangiogenic effects of flavonoids and chalcones

J Mojzis, L Varinska, G Mojzisova, I Kostova… - Pharmacological …, 2008 - Elsevier
Angiogenesis, the development of new blood vessels from the existing vasculature, is
essential in normal developmental processes. Uncontrolled angiogenesis is a major …

Site-specific anticancer effects of dietary flavonoid quercetin

K Sak - Nutrition and cancer, 2014 - Taylor & Francis
Food-derived flavonoid quercetin, widely distributed in onions, apples, and tea, is able to
inhibit growth of various cancer cells indicating that this compound can be considered as a …

[HTML][HTML] Quercetin inhibits the proliferation of glycolysis-addicted HCC cells by reducing hexokinase 2 and Akt-mTOR pathway

H Wu, L Pan, C Gao, H Xu, Y Li, L Zhang, L Ma, L Meng… - Molecules, 2019 - mdpi.com
Increased glycolysis in tumor cells is associated with increased risk of tumor progression
and mortality. Therefore, disruption of glycolysis, one of the main sources of cellular energy …

Complementary and alternative medicine: herbs, phytochemicals and vitamins and their immunologic effects

T Mainardi, S Kapoor, L Bielory - Journal of Allergy and Clinical …, 2009 - Elsevier
Complementary and alternative medicines (CAMs) are used in more than 80% of the world's
population and are becoming an increasing component of the US health care system, with …