Over the past year, numerous studies in the peer reviewed and preprint literature have
reported on the virological, epidemiological and clinical characteristics of the coronavirus …

Checkpoint inhibitor-based immunotherapies that target cytotoxic T lymphocyte antigen 4
(CTLA4) or the programmed cell death 1 (PD1) pathway have achieved impressive success …

Efforts are being made worldwide to understand the immune response to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus …

CD8+ T cell–dependent killing of cancer cells requires efficient presentation of tumor
antigens by human leukocyte antigen class I (HLA-I) molecules. However, the extent to …

Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
developing pathogen‐specific memory that confers immunological protection. Memory and …

The role of CD8+ T cells in dengue virus infection and subsequent disease manifestations is
not fully understood. According to the original antigenic sin theory, skewing of T-cell …

T cells are a critical part of the adaptive immune system that are able to distinguish between
healthy and unhealthy cells. Upon recognition of protein fragments (peptides), activated T …

Dengue virus (DENV) is a rapidly spreading pathogen with unusual pathogenesis, and
correlates of protection from severe dengue disease and vaccine efficacy have not yet been …

In this paper we describe an improved neural network method to predict T‐cell class I
epitopes. A novel input representation has been developed consisting of a combination of …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
that escape convalescent and vaccine-induced antibody responses has renewed focus on …