New-age vaccine adjuvants, their development, and future perspective
In the present scenario, immunization is of utmost importance as it keeps us safe and
protects us from infectious agents. Despite the great success in the field of vaccinology …
protects us from infectious agents. Despite the great success in the field of vaccinology …
[HTML][HTML] Polysaccharide-based nanomedicines for cancer immunotherapy: A review
Cancer immunotherapy is an effective antitumor approach through activating immune
systems to eradicate tumors by immunotherapeutics. However, direct administration of …
systems to eradicate tumors by immunotherapeutics. However, direct administration of …
Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling
H Zhang, X You, X Wang, L Cui… - Proceedings of the …, 2021 - National Acad Sciences
Intracellular delivery of messenger RNA (mRNA)-based cancer vaccine has shown great
potential to elicit antitumor immunity. To achieve robust antitumor efficacy, mRNA encoding …
potential to elicit antitumor immunity. To achieve robust antitumor efficacy, mRNA encoding …
Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice
Synthetic mRNA represents an exciting cancer vaccine technology for the implementation of
effective cancer immunotherapy. However, inefficient in vivo mRNA delivery along with a …
effective cancer immunotherapy. However, inefficient in vivo mRNA delivery along with a …
Mechanisms of macrophage plasticity in the tumor environment: manipulating activation state to improve outcomes
TD Ricketts, N Prieto-Dominguez, PS Gowda… - Frontiers in …, 2021 - frontiersin.org
Macrophages are a specialized class of innate immune cells with multifaceted roles in
modulation of the inflammatory response, homeostasis, and wound healing. While …
modulation of the inflammatory response, homeostasis, and wound healing. While …
Development and validation of a robust ferroptosis-related prognostic signature in lung adenocarcinoma
A Zhang, J Yang, C Ma, F Li, H Luo - Frontiers in Cell and …, 2021 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell
lung cancer. Ferroptosis is a newly recognized process of cell death, which is different from …
lung cancer. Ferroptosis is a newly recognized process of cell death, which is different from …
Potential effects of gut microbiota on host cancers: focus on immunity, DNA damage, cellular pathways, and anticancer therapy
J Sun, F Chen, G Wu - The ISME Journal, 2023 - academic.oup.com
The symbiotic bacteria that live in the human gut and the metabolites they produce have
long influenced local and systemic physiological and pathological processes of the host …
long influenced local and systemic physiological and pathological processes of the host …
An overview of nanocarrier-based adjuvants for vaccine delivery
KC Petkar, SM Patil, SS Chavhan, K Kaneko… - Pharmaceutics, 2021 - mdpi.com
The development of vaccines is one of the most significant medical accomplishments which
has helped to eradicate a large number of diseases. It has undergone an evolutionary …
has helped to eradicate a large number of diseases. It has undergone an evolutionary …
Fluoroalkane modified cationic polymers for personalized mRNA cancer vaccines
J Li, Y Wu, J Xiang, H Wang, Q Zhuang, T Wei… - Chemical Engineering …, 2023 - Elsevier
Messenger RNA (mRNA) vaccines, while demonstrating great successes in the fight against
COVID-19, have been extensively studied in other areas such as personalized cancer …
COVID-19, have been extensively studied in other areas such as personalized cancer …
Therapeutic targeting of TLR4 for inflammation, infection, and cancer: a perspective for disaccharide lipid A mimetics
H Heine, A Zamyatina - Pharmaceuticals, 2022 - mdpi.com
The Toll-like receptor 4 (TLR4) signaling pathway plays a central role in the prompt defense
against infectious challenge and provides immediate response to Gram-negative bacterial …
against infectious challenge and provides immediate response to Gram-negative bacterial …