Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …

Oxidative stress is significantly involved in the pathogenesis and progression of chronic
obstructive pulmonary disease (COPD). Combining antioxidant drugs or nutrients results in …

Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ
diseases owing to its high content of harmful chemicals and reactive oxygen species (ROS) …

Current guidelines recommend inhaled pharmacologic therapy as the preferred route of
administration for treating COPD. Bronchodilators (β2-agonists and antimuscarinics) are the …

Chronic obstructive pulmonary disease (COPD) remains a leading cause of death
worldwide, yet only one new drug class has been approved in the last decade. However …

Objective To determine the cytotoxicity, reduction in nitric oxide production and anti-
oxidative activity of the aqueous leaf extract from Tithonia diversifolia (T. diversifolia) in an in …

Background Revefenacin is a once-daily long-acting muscarinic antagonist (LAMA) in
clinical development for the treatment of patients with chronic obstructive pulmonary disease …

Purpose The burden associated with chronic obstructive pulmonary disease (COPD) is
substantial. The objectives of this study were to describe healthcare resource utilization …

Background and purpose Fixed-dose combinations of a long-acting beta agonist and an
inhaled corticosteroid are more effective than the individual components in COPD. The …

Objective The potential effects of nitrate in patients with chronic obstructive pulmonary
disease (COPD) have attracted increased research interest. However, previous clinical trials …