Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

The purpose of this review is to outline recent trends in contrast agent development for
magnetic resonance imaging. Up to now, small molecular weight gadolinium chelates are …

Established as the leading textbook on imaging diagnosis of brain and spine disorders,
Magnetic Resonance Imaging of the Brain and Spine is now in its Fourth Edition. This …

Large macromolecular MRI contrast agents with albumin or dendrimer cores are useful for
imaging blood vessels. However, their prolonged retention is a major limitation for clinical …

Ongoing developments in contrast media for magnetic resonance (MR) imaging should lead
to an improvement in sensitivity for the detection of disease, better definition of normal and …

Nuclear magnetic resonance (NMR) imaging has been shown to accurately portray cardiac
anatomy and function. To investigate the potential of NMR imaging for the assessment of …

Rationale and Objectives The authors evaluate MS-325, a new albumin-targeted magnetic
resonance imaging (MRI) contrast agent, for its pharmacokinetics, biodistribution, and …

MRI enhanced with a macromolecular contrast medium (MMCM) has previously been
shown to estimate tumor microvascular characteristics that correlate closely with histologic …

The authors assessed the clinical utility of a magnetic resonance angiography technique in
the evaluation of intracranial circulation. Eighteen patients with a low likelihood of …

Four novel macromolecular MRI contrast agents, all of which had the same chemical
composition but different molecular weights, were prepared using generation‐3,‐4,‐5, and …