Background Children with rs9939609 FTO variant alleles (homozygous= AA and
heterozygous= AT) are predisposed to greater adiposity than are those with 2 wild-type …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Objective: Polymorphisms in the obesity-associated gene, FTO, have been linked with
sensitivity to satiety in children, indicating FTO may be influencing one of the regulatory …

Background The fat mass and obesity–associated gene (FTO) has been shown to be
associated with obesity and to influence appetite regulation. Objective The aim was to …

FTO (fat mass and obesity associated) was identified as an obesity-susceptibility gene by
several independent large-scale genome association studies. A cluster of SNPs (single …

The Fat mass and obesity associated (FTO) gene is a newly identified genetic factor for
obesity. However, the exact molecular mechanisms responsible for the effect of FTO on …

Obesity, particularly central adiposity, is the primary causal factor in the development of
insulin resistance, the hallmark of the metabolic syndrome (MetS), a common condition …

SNPs in the first intron of FTO (fat mass and obesity associated) are strongly associated with
human obesity. While it is not yet formally established that this effect is mediated through the …

Common polymorphisms in the first intron of FTO are associated with increased body weight
in adults. Previous studies have suggested that a CUX1-regulatory element within the …

An age-dependent association between variation at the FTO locus and BMI in children has
been suggested. We meta-analyzed associations between the FTO locus (rs9939609) and …