Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

This tutorial review covers the recent advances made in the study of gold complexes
containing N-heterocyclic carbene ligands with biological properties. The great stability …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

Highlights•Metal-NHC complexes have their metal centers stabilized under physiological
conditions and can exhibit anticancer activity.•Metal-NHC complexes having new …

The DNA G-quadruplex is known for forming a range of topologies and for the observed
lability of the assembly, consistent with its transient formation in live cells. The stabilization of …

Metal N‐heterocyclic carbene (NHC) complexes are a promising class of anti‐cancer agents
displaying potent in vitro and in vivo activities. Taking a multi‐faceted approach employing …

Conspectus Over the past few decades, research on the chemistry of gold has progressed
rapidly, encompassing topics like catalysis, supramolecular chemistry, molecular …

In recent years, gold compounds have gained more and more attentions in the design of
new metal anticancer drugs. Numerous researches have reported that gold compounds, in …

The discovery of the medicinal properties of platinum complexes has fueled the design and
synthesis of new anticancer metallodrugs endowed with unique modes of action (MoA) …