Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19)

S Umakanthan, P Sahu, AV Ranade… - Postgraduate …, 2020 - academic.oup.com
Coronavirus has emerged as a global health threat due to its accelerated geographic
spread over the last two decades. This article reviews the current state of knowledge …

[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

E Shrock, E Fujimura, T Kula, RT Timms, IH Lee… - Science, 2020 - science.org
INTRODUCTION A systematic characterization of the humoral response to severe acute
respiratory system coronavirus 2 (SARS-CoV-2) epitopes has yet to be performed. This …

[HTML][HTML] Zoonotic diseases: etiology, impact, and control

MT Rahman, MA Sobur, MS Islam, S Ievy, MJ Hossain… - Microorganisms, 2020 - mdpi.com
Most humans are in contact with animals in a way or another. A zoonotic disease is a
disease or infection that can be transmitted naturally from vertebrate animals to humans or …

[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

[HTML][HTML] Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations …

H Chu, JFW Chan, TTT Yuen, H Shuai, S Yuan… - The Lancet …, 2020 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported
from China in January, 2020. SARS-CoV-2 is efficiently transmitted from person to person …

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

COVID‐19 patients' clinical characteristics, discharge rate, and fatality rate of meta‐analysis

L Li, T Huang, Y Wang, Z Wang, Y Liang… - Journal of medical …, 2020 - Wiley Online Library
The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of
COVID‐19 patients for clinical help. The clinical data of COVID‐19 patients from December …

Coronavirus disease 2019: What we know?

F He, Y Deng, W Li - Journal of medical virology, 2020 - Wiley Online Library
In late December 2019, a cluster of unexplained pneumonia cases has been reported in
Wuhan, China. A few days later, the causative agent of this mysterious pneumonia was …

Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study

AA Elfiky - Life sciences, 2020 - Elsevier
Aims A new human coronavirus (HCoV), which has been designated SARS-CoV-2, began
spreading in December 2019 in Wuhan City, China causing pneumonia called COVID-19 …