Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

Glutamate-mediated excitotoxicity is an important mechanism leading to post ischemic
stroke damage. After acute stroke, the sudden reduction in cerebral blood flow is most …

Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …

Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …

Cannabinoids have a long record of recreational and medical use and become increasingly
approved for pain therapy. This development is based on preclinical and human …

Background: Cannabidiol (CBD) is among the major secondary metabolites of Cannabis
devoid of the delta-9-tetra-hydrocannabinol psychoactive effects. It is a resorcinol-based …

One of the main non-psychoactive phytocannabinoids of cannabis is cannabidiol (CBD),
which has attracted much attention for its neuroprotective roles. The present study was …

Glia form a central component of the nervous system whose varied activities sustain an
environment that is optimised for healthy development and neuronal function. Alpha-amino …

Ischemia/reperfusion (I/R) injury is a pathological process wherein reperfusion of an
ischemic organ or tissue exacerbates the injury, posing a significant health threat and …

Toll-like receptors (TLRs) are sensors of pathogen-associated molecules that trigger
inflammatory signalling in innate immune cells including macrophages. All TLRs, with the …