Importance Many women spend a substantial proportion of their lives preventing or planning
for pregnancy, and approximately 87% of US women use contraception during their lifetime …

Background Combined oral contraceptive (COC) use has been associated with venous
thrombosis (VT)(ie, deep venous thrombosis and pulmonary embolism). The VT risk has …

Objective To provide a comprehensive overview of the risk of venous thrombosis in women
using different combined oral contraceptives. Design Systematic review and network meta …

Objective To assess efficacy, cycle control, and safety of an oral contraceptive containing
estetrol (E4) 15 mg and drospirenone (DRSP) 3 mg. Study design Women aged 16 to 50 …

The need to seek improved combined oral contraceptive (COC) efficacy, with fewer health
risks and better acceptability, has been ongoing since the introduction of COCs more than …

BACKGROUND In recent years, several new oral contraceptives have become available. In
some ways, they represent an evolution in terms of individualization and compliance on the …

BACKGROUND: This article is a comprehensive overview of dysmenorrhea and a
systematic review of the available literature on the use of nonsteroidal anti-inflammatory …

Importance Meta-analyses have reported conflicting data on the safety of hormonal
contraception, but the quality of evidence for the associations between hormonal …

Background Menstrual irregularity (MI) is common in female athletes and is a component of
the Female Athlete Triad (Triad). Many athletes with the Triad are started on hormonal …

In the 50 years since the advent of combined oral contraceptives the amount of estrogen in
oral contraceptives dropped from over 100 mcg to less than 30 mcg. Many noncontraceptive …