Mechanisms and Drug Intervention for Doxorubicin‐Induced Cardiotoxicity Based on Mitochondrial Bioenergetics

G Ling, X Wang, N Tan, J Cao, W Li… - Oxidative Medicine …, 2022 - Wiley Online Library
Doxorubicin (DOX) is an anthracycline chemotherapy drug, which is indispensable in
antitumor therapy. However, its subsequent induction of cardiovascular disease (CVD) has …

Ferulic acid alleviates myocardial ischemia reperfusion injury via upregulating AMPKα2 expression-mediated ferroptosis depression

X Liu, K Qi, Y Gong, X Long, S Zhu, F Lu… - Journal of …, 2022 - journals.lww.com
Ferroptosis, a recently discovered form of regulated cell death that is characterized by iron
accumulation and excessive reactive oxygen species generation, has been favored by most …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

A mechanistic exploration of the metabolome of African mango seeds and its potential to alleviate cognitive impairment induced by high-fat/high-carbohydrate diets …

YR Hassan, RA El-Shiekh, HM El Hefnawy… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Irvingia gabonensis (Aubry-Lecomte ex O'Rorke)
Baill., also known as “African mango” or “bush mango”, belonging to family Irvingiaceae, has …

Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activity of the Irvingia Species

BN Nguena-Dongue, B Pone Kamdem… - Drugs and Drug …, 2023 - mdpi.com
Plants belonging to the genus Irvingia are widespread across the African and Southeast
Asian regions of the world. Irvingia gabonensis, Irvingia malayana, and Irvingia grandifolia …

Evaluation of chemical composition, in vitro antioxidant, and antidiabetic activities of solvent extracts of Irvingia gabonensis leaves

FO Atanu, A Ikeojukwu, PA Owolabi, OJ Avwioroko - Heliyon, 2022 - cell.com
Irvingia gabonensis commonly referred to as wild mango or ogbono is a tropical plant with
both nutritional and medicinal uses. The present study was designed to evaluate the …

[HTML][HTML] Role of diosmin in preventing doxorubicin-induced cardiac oxidative stress, inflammation, and hypertrophy: A mechanistic approach

AF AlAsmari, MM Al-Shehri, N Algarini… - Saudi Pharmaceutical …, 2024 - Elsevier
Chemotherapeutic drugs, such as doxorubicin (Dox), are commonly used to treat a variety of
malignancies. However, Dox-induced cardiotoxicity limits the drug's clinical applications …

[HTML][HTML] The metabolomics analysis of cecal contents elucidates significant metabolites involved in the therapeutic effects of total flavonoids derived from Sonchus …

N Chang, S Wang, S Hou, Y Sui, J He, Y Ren, G Chen… - Heliyon, 2024 - cell.com
Ulcerative colitis (UC), an inflammatory disease affecting the colon and rectal mucosa, is
characterized by chronic and heterogeneous behavior of unknown origin. The primary …

Improvement of stability and in vivo antioxidant effect of human glutathione peroxidase mutant by PEGylation

Y Wang, S Niu, B Li, Q Yan, Y Zhao, Z Wang… - International Journal of …, 2021 - Elsevier
Human glutathione peroxidase (GPx), as an important kind of antioxidant enzyme, is often
used for the removal of reactive oxygen species. Unfortunately, the application has been …

Botanical and Bioactive Markers of Nigerian Bitter Honey.

BO Adeoye, AA Iyanda, MO Daniyan… - Tropical Journal of …, 2022 - search.ebscohost.com
Honey is a central medium wherein plant-based chemicals are expressed. Its
pharmacological value usually varies from one vegetal origin to another. The botanical …