[HTML][HTML] Comparative ochratoxin toxicity: A review of the available data

AH Heussner, LEH Bingle - Toxins, 2015 - mdpi.com
Ochratoxins are a group of mycotoxins produced by a variety of moulds. Ochratoxin A (OTA),
the most prominent member of this toxin family, was first described by van der Merwe et al. in …

[HTML][HTML] Toxicity of ochratoxin A and its modulation by antioxidants: A review

V Sorrenti, C Di Giacomo, R Acquaviva, I Barbagallo… - Toxins, 2013 - mdpi.com
Ochratoxin A (OTA) is a mycotoxin involved in the development of different types of cancers
in rats, mice and humans. A growing number of in vitro and in vivo studies has been …

Toxicity testing in the 21st century: a vision and a strategy

D Krewski, D Acosta Jr, M Andersen… - Journal of Toxicology …, 2010 - Taylor & Francis
With the release of the landmark report Toxicity Testing in the 21st Century: A Vision and a
Strategy, the US National Academy of Sciences, in 2007, precipitated a major change in the …

Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints

JG Costa, N Saraiva, PS Guerreiro, H Louro… - Food and Chemical …, 2016 - Elsevier
Ochratoxin A (OTA) is a well-known nephrotoxic and potential carcinogenic agent but no
consensus about the molecular mechanisms underlying its deleterious effects has been …

Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review

J Tabeshpour, S Mehri… - Phytotherapy …, 2018 - Wiley Online Library
Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a
valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its …

Ochratoxin A carcinogenicity involves a complex network of epigenetic mechanisms

M Marin-Kuan, C Cavin, T Delatour, B Schilter - Toxicon, 2008 - Elsevier
Ochratoxin A (OTA) is a mycotoxin occurring in a wide range of food products. Because of
the limitation of human epidemiological data, the safety significance of OTA in food has to …

[HTML][HTML] Deficient glutathione in the pathophysiology of mycotoxin-related illness

FT Guilford, J Hope - Toxins, 2014 - mdpi.com
Evidence for the role of oxidative stress in the pathophysiology of mycotoxin-related illness
is increasing. The glutathione antioxidant and detoxification systems play a major role in the …

Ochratoxin A: 13-week oral toxicity and cell proliferation in male F344/N rats

E Rached, GC Hard, K Blumbach, K Weber… - Toxicological …, 2007 - academic.oup.com
Ochratoxin A (OTA) is nephrotoxic and a potent renal carcinogen. Male rats are most
susceptible to OTA toxicity, and chronic administration of OTA (70 and 210 μg/kg bw) for 2 …

Molecular signatures of cytotoxic effects in human embryonic kidney 293 cells treated with single and mixture of ochratoxin A and citrinin

L Gong, H Zhu, T Li, G Ming, X Duan, J Wang… - Food and Chemical …, 2019 - Elsevier
Ochratoxin A (OTA) and citrinin (CTN) are important mycotoxins, which often coexist in food
and feed stuff. In this study, individual and combinative cytotoxicity of OTA and CTN were …

Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin A

M Marin-Kuan, V Ehrlich, T Delatour… - Journal of …, 2011 - Wiley Online Library
The in vitro and in vivo evidence compatible with a role for oxidative stress in OTA
carcinogenicity has been collected and described. Several potential oxido‐reduction …