Advances in cell-based therapy, particularly CAR-T cell therapy, have transformed the
treatment of hematological malignancies. Although an important step forward for the field …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Simple Summary Induced pluripotent stem cells (iPSCs) that can be genetically engineered
and differentiated into different types of immune cells, providing an unlimited resource for …

Chimeric antigen receptor-T (CAR-T) cell therapy, as a novel cellular immunotherapy, has
dramatically reshaped the landscape of cancer treatment, especially in hematological …

Advanced gene transfer technologies and profound immunological insights have enabled
substantial increases in the efficacy of anticancer adoptive cellular therapy (ACT). In recent …

Simple Summary The ultimate goal of T cell-engaging immunotherapy is to endorse the
activity of a person's own cytotoxic T cells in the tumor microenvironment, finally destroying …

Induced pluripotent stem cells (iPSCs) are remarkable scientific advances in both
regenerative and personalized medicine. Since they were first reported in 2006, iPSCs have …

Chimeric antigen receptor (CAR)-immune cell therapy has revolutionized the anti-tumor
field, achieving efficient and precise tumor clearance by directly guiding immune cell activity …

Adoptive cell immunotherapy with chimeric antigen receptor T (CAR‐T) cell has brought a
revolutionary means of treatment for aggressive diseases such as hematologic …

Simple Summary Cancer treatments are evolving at a very rapid pace. Some of the most
novel anti-cancer medicines under development rely on the modification of immune cells in …