[HTML][HTML] New insights into the role and mechanisms of ginsenoside Rg1 in the management of Alzheimer's disease

J Wu, Y Yang, Y Wan, J Xia, JF Xu, L Zhang… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is a common neurodegenerative disorder in the elderly
characterized by memory loss and cognitive dysfunction. The pathogenesis of AD is …

Therapeutic potential of phenylethanoid glycosides: A systematic review

L Wu, MI Georgiev, H Cao, L Nahar… - Medicinal Research …, 2020 - Wiley Online Library
Phenylethanoid glycosides (PhGs) are generally water‐soluble phenolic compounds that
occur in many medicinal plants. Until June 2020, more than 572 PhGs have been isolated …

Adiponectin and cognitive decline

MR Rizzo, R Fasano, G Paolisso - International journal of molecular …, 2020 - mdpi.com
Adiponectin (ADPN) is a plasma protein secreted by adipose tissue showing pleiotropic
effects with anti-diabetic, anti-atherogenic, and anti-inflammatory properties. Initially, it was …

Advances in polysaccharides of natural source of the anti-Alzheimer's disease effect and mechanism

Z Zhang, S Wang, H Tan, P Yang, Y Li, L Xu… - Carbohydrate …, 2022 - Elsevier
Alzheimer's disease (AD) is a complex neurodegenerative disorder. The pathology is
characterized by the generation of amyloid plaques and neuronal fiber tangles in the brain …

Metformin Ameliorates Aβ Pathology by Insulin‐Degrading Enzyme in a Transgenic Mouse Model of Alzheimer's Disease

XY Lu, S Huang, QB Chen, D Zhang… - Oxidative medicine …, 2020 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative disease. The
accumulation of amyloid beta (Aβ) is the main pathology of AD. Metformin, a well‐known …

Obesity and Alzheimer's disease: Molecular bases

P Picone, M Di Carlo, D Nuzzo - European Journal of …, 2020 - Wiley Online Library
Obesity is a complex, chronic, and multifactorial condition characterized by abnormal fat
accumulation in tissues and organs and inducing negative effects on human health …

[HTML][HTML] Dendrimers and derivatives as multifunctional nanotherapeutics for Alzheimer's disease

DA Moreira, SD Santos, V Leiro, AP Pêgo - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. It affects more than 30
million people worldwide and costs over US $1.3 trillion annually. AD is characterized by the …

Alzheimer's disease: The role of proteins in formation, mechanisms, and new therapeutic approaches

A Gholami - Neuroscience Letters, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurological disorder that affects the central
nervous system (CNS), leading to memory and cognitive decline. In AD, the brain …

Interactions of amyloid-β with membrane proteins

B Wiatrak, J Piasny, A Kuźniarski… - International journal of …, 2021 - mdpi.com
In developing and developed countries, an increasing elderly population is observed. This
affects the growing percentage of people struggling with neurodegenerative diseases …

Insulin and its key role for mitochondrial function/dysfunction and quality control: a shared link between dysmetabolism and neurodegeneration

G Galizzi, M Di Carlo - Biology, 2022 - mdpi.com
Simple Summary This review will comprise an overview of insulin and its history, structure,
synthesis, secretion, signaling, and peripheral and brain roles. Further, the impact that …