[HTML][HTML] Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
[HTML][HTML] Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics
Y Duan, K Gong, S Xu, F Zhang, X Meng… - Signal Transduction and …, 2022 - nature.com
Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
Mechanisms and regulation of cholesterol homeostasis
Cholesterol homeostasis is vital for proper cellular and systemic functions. Disturbed
cholesterol balance underlies not only cardiovascular disease but also an increasing …
cholesterol balance underlies not only cardiovascular disease but also an increasing …
[HTML][HTML] Protein-based nanoparticles as drug delivery systems
Nanoparticles have been extensively used as carriers for the delivery of chemicals and
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …
Gut microbially produced indole-3-propionic acid inhibits atherosclerosis by promoting reverse cholesterol transport and its deficiency is causally related to …
H Xue, X Chen, C Yu, Y Deng, Y Zhang… - Circulation …, 2022 - Am Heart Assoc
Background: Accumulating evidence has shown that disorders in the gut microbiota and
derived metabolites affect the development of atherosclerotic cardiovascular disease …
derived metabolites affect the development of atherosclerotic cardiovascular disease …
Lipid and lipoprotein metabolism
KR Feingold - Endocrinology and Metabolism Clinics, 2022 - endo.theclinics.com
Lipids are insoluble in water and therefore cholesterol and triglycerides need to be
transported in association with proteins (ie, lipoproteins) in the bloodstream. Lipoproteins …
transported in association with proteins (ie, lipoproteins) in the bloodstream. Lipoproteins …
Cholesterol metabolism: new functions and therapeutic approaches in cancer
H Xu, S Zhou, Q Tang, H Xia, F Bi - … et Biophysica Acta (BBA)-Reviews on …, 2020 - Elsevier
Cholesterol and its metabolites (precursors and derivatives) play an important role in cancer.
In recent years, numerous studies have reported the functions of cholesterol metabolism in …
In recent years, numerous studies have reported the functions of cholesterol metabolism in …
High-density lipoproteins, reverse cholesterol transport and atherogenesis
HJ Pownall, C Rosales, BK Gillard… - Nature Reviews …, 2021 - nature.com
Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …
Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis
H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …
representing the most common chronic liver disease in the world. Atherosclerotic …
Role of estrogens in the regulation of liver lipid metabolism
Before menopause, women are protected from atherosclerotic heart disease associated with
obesity relative to men. Sex hormones have been proposed as a mechanism that …
obesity relative to men. Sex hormones have been proposed as a mechanism that …