Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

Cholesterol homeostasis is vital for proper cellular and systemic functions. Disturbed
cholesterol balance underlies not only cardiovascular disease but also an increasing …

Nanoparticles have been extensively used as carriers for the delivery of chemicals and
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …

Background: Accumulating evidence has shown that disorders in the gut microbiota and
derived metabolites affect the development of atherosclerotic cardiovascular disease …

Lipids are insoluble in water and therefore cholesterol and triglycerides need to be
transported in association with proteins (ie, lipoproteins) in the bloodstream. Lipoproteins …

Cholesterol and its metabolites (precursors and derivatives) play an important role in cancer.
In recent years, numerous studies have reported the functions of cholesterol metabolism in …

Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …

Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Before menopause, women are protected from atherosclerotic heart disease associated with
obesity relative to men. Sex hormones have been proposed as a mechanism that …