Activation of PI3K/AKT/mTOR pathway causes drug resistance in breast cancer
C Dong, J Wu, Y Chen, J Nie, C Chen - Frontiers in pharmacology, 2021 - frontiersin.org
Although chemotherapy, targeted therapy and endocrine therapy decrease rate of disease
recurrence in most breast cancer patients, many patients exhibit acquired resistance …
recurrence in most breast cancer patients, many patients exhibit acquired resistance …
[HTML][HTML] Drug resistance in metastatic breast cancer: tumor targeted nanomedicine to the rescue
Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …
LncRNAs in breast cancer: a link to future approaches
N Sideris, P Dama, S Bayraktar, T Stiff… - Cancer gene …, 2022 - nature.com
Breast cancer affects millions of women each year. Despite recent advances in targeted
treatments breast cancer remains a significant threat to women's health. In recent years the …
treatments breast cancer remains a significant threat to women's health. In recent years the …
Signaling pathways governing breast cancer stem cells behavior
K Song, M Farzaneh - Stem Cell Research & Therapy, 2021 - Springer
Breast cancer is the second common cancer and the leading cause of malignancy among
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …
[HTML][HTML] A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer
Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
Resistance and overcoming resistance in breast cancer
A Luque-Bolivar, E Pérez-Mora… - … Cancer: Targets and …, 2020 - Taylor & Francis
The incidence and mortality of breast cancer (BC) have increased in recent years, and BC is
the main cause of cancer-related death in women worldwide. One of the most significant …
the main cause of cancer-related death in women worldwide. One of the most significant …
SLC7A11/xCT is a target of miR-5096 and its restoration partially rescues miR-5096-mediated ferroptosis and anti-tumor effects in human breast cancer cells
Breast cancer cells evade cell death by overexpressing SLC7A11, which functions by
transporting cystine into cells in exchange for intracellular glutamate facilitating glutathione …
transporting cystine into cells in exchange for intracellular glutamate facilitating glutathione …
[HTML][HTML] Hesperidin and its aglycone hesperetin in breast cancer therapy: A review of recent developments and future prospects
Breast cancer (BC) has high incidence and mortality rates, making it a major global health
issue. BC treatment has been challenging due to the presence of drug resistance and the …
issue. BC treatment has been challenging due to the presence of drug resistance and the …
Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action
M Behroozaghdam, M Dehghani, A Zabolian… - Cellular and Molecular …, 2022 - Springer
Breast cancer (BC) is one of the most common cancers in females and is responsible for the
highest cancer-related deaths following lung cancer. The complex tumor microenvironment …
highest cancer-related deaths following lung cancer. The complex tumor microenvironment …
Plasmin and plasminogen system in the tumor microenvironment: implications for cancer diagnosis, prognosis, and therapy
AG Bharadwaj, RW Holloway, VA Miller, DM Waisman - Cancers, 2021 - mdpi.com
Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …
activation system is utilized by tumor cells in their unrelenting attack on the tissues …