A review of reported tissue optical properties summarizes the wavelength-dependent
behavior of scattering and absorption. Formulae are presented for generating the optical …

Although modern techniques such as two-photon microscopy can now provide cellular-level
three-dimensional imaging of the intact living brain, the speed and fields of view of these …

This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

The recent developments in time-domain diffuse optics that rely on physical concepts (eg,
time-gating and null distance) and advanced photonic components (eg, vertical cavity …

Near-infrared spectroscopy (NIRS) measurements of cytochrome-c-oxidase (CCO) have the
potential to yield crucial information about cerebral metabolism at the patient bedside …

This review celebrates the 30th anniversary of the first in vivo near-infrared (NIR)
spectroscopy (NIRS) publication, which was authored by Professor Frans Jöbsis. At first …

The authors describe the development of diffuse optical imaging (DOI) technologies,
specifically the use of spatial and temporal modulation to control near infrared light …

This article reviews the basic principles of frequency-domain near-infrared spectroscopy (FD-
NIRS), which relies on intensity-modulated light sources and phase-sensitive optical …

Diffuse optical imaging and spectroscopy of the female breast is an area of active research.
We review the present status of this field and discuss the broad range of methodologies and …

Diffuse optical imaging (DOI) may be a beneficial diagnostic method for women with
mammographically dense breast tissue. In order to evaluate the utility of DOI, we are …