Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents

T Luger, M Amagai, B Dreno, MA Dagnelie… - Journal of …, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by eczematous
and pruritic skin lesions. In recent decades, the prevalence of AD has increased worldwide …

Atopic dermatitis in diverse racial and ethnic groups—variations in epidemiology, genetics, clinical presentation and treatment

BP Kaufman, E Guttman‐Yassky… - Experimental …, 2018 - Wiley Online Library
Atopic dermatitis (AD) is a chronic inflammatory skin condition that affects diverse ethnic
groups with varying prevalence. Despite a predominance of studies in individuals of …

Racial differences in atopic dermatitis

PM Brunner, E Guttman-Yassky - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
Objective To summarize studies investigating ethnical and racial differences in atopic
dermatitis (AD) epidemiology, clinical features, and skin and blood phenotypes. Data …

[HTML][HTML] Claudin-1 decrease impacts epidermal barrier function in atopic dermatitis lesions dose-dependently

S Bergmann, B von Buenau, S Vidal-y-Sy, M Haftek… - Scientific reports, 2020 - nature.com
The transmembrane protein claudin-1 is a major component of epidermal tight junctions
(TJs), which create a dynamic paracellular barrier in the epidermis. Claudin-1 …

[HTML][HTML] Genetics and epigenetics of atopic dermatitis: an updated systematic review

MJ Martin, M Estravís, A García-Sánchez, I Dávila… - Genes, 2020 - mdpi.com
Background: Atopic dermatitis is a common inflammatory skin disorder that affects up to 15–
20% of the population and is characterized by recurrent eczematous lesions with intense …

Skin barrier defects in atopic dermatitis: From old idea to new opportunity

T Yoshida, LA Beck, A De Benedetto - Allergology International, 2022 - jstage.jst.go.jp
abstract Atopic dermatitis (AD) is the most common chronic skin inflammatory disease, with a
profound impact on patients' quality of life. AD varies considerably in clinical course, age of …

Endophenotypic variations of atopic dermatitis by age, race, and ethnicity

T Nomura, J Wu, K Kabashima… - The Journal of Allergy and …, 2020 - Elsevier
Atopic dermatitis (AD) is a heterogeneous disease with unique clinical manifestations across
age groups and race/ethnicities. Characteristic molecular mechanisms, known as …

Diagnosing atopic dermatitis in skin of color

W Adawi, H Cornman, A Kambala, S Henry… - Dermatologic …, 2023 - derm.theclinics.com
Atopic Dermatitis (AD) is an extremely pruritic inflammatory skin disease that has a
worldwide prevalence of approximately 2.69%, with significant variability by country. 1 In the …

[HTML][HTML] Overview of atopic dermatitis in different ethnic groups

A Chiricozzi, M Maurelli, L Calabrese, K Peris… - Journal of Clinical …, 2023 - mdpi.com
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a high
prevalence worldwide, including countries from Asia, Africa, and Latin America, and in …

Tight junctions in skin inflammation

K Bäsler, JM Brandner - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
Inflammation of the skin is found after various external stimuli, eg, UV radiation, allergen
uptake, microbial challenge, or contact with irritants, as well as due to intrinsic, not always …