Exercise capacity in single-ventricle patients after Fontan correlates with haemodynamic energy loss in TCPC

RH Khiabani, KK Whitehead, D Han, M Restrepo… - Heart, 2015 - heart.bmj.com
Objective Elevated energy loss in the total cavopulmonary connection (TCPC) is
hypothesised to have a detrimental effect on clinical outcomes in single-ventricle physiology …

Respiratory effects on Fontan circulation during rest and exercise using real-time cardiac magnetic resonance imaging

Z Wei, KK Whitehead, RH Khiabani, M Tree… - The Annals of thoracic …, 2016 - Elsevier
Background It is known that respiration modulates cavopulmonary flows, but little data
compare mean flows under breath-holding and free-breathing conditions to isolate the …

Regional variation of wall shear stress in ascending thoracic aortic aneurysms

A Rinaudo, S Pasta - … , Part H: Journal of Engineering in …, 2014 - journals.sagepub.com
The development of an ascending thoracic aortic aneurysm is likely caused by excessive
hemodynamic loads exerted on the aneurysmal wall. Computational fluid-dynamic analyses …

Computer-aided patient-specific coronary artery graft design improvements using CFD coupled shape optimizer

O Dur, ST Coskun, KO Coskun, D Frakes… - Cardiovascular …, 2011 - Springer
This study aims to (i) demonstrate the efficacy of a new surgical planning framework for
complex cardiovascular reconstructions,(ii) develop a computational fluid dynamics (CFD) …

[HTML][HTML] Computer modeling for the prediction of thoracic aortic stent graft collapse

S Pasta, JS Cho, O Dur, K Pekkan, DA Vorp - Journal of vascular surgery, 2013 - Elsevier
OBJECTIVE: To assess the biomechanical implications of excessive stent protrusion into the
aortic arch in relation to thoracic aortic stent graft (TASG) collapse by simulating the …

Hemodynamic study of TCPC using in vivo and in vitro 4D Flow MRI and numerical simulation

A Roldán-Alzate, S García-Rodríguez… - Journal of …, 2015 - Elsevier
Introduction: Altered total cavopulmonary connection (TCPC) hemodynamics can cause
long-term complications. Patient-specific anatomy hinders generalized solutions. 4D Flow …

Biomechanical implications of excessive endograft protrusion into the aortic arch after thoracic endovascular repair

A Rinaudo, GM Raffa, F Scardulla, M Pilato… - Computers in biology …, 2015 - Elsevier
Endografts placed in the aorta for thoracic endovascular aortic repair (TEVAR) may
determine malappositioning to the lesser curvature of the aortic wall, thus resulting in a …

[HTML][HTML] In vitro validation of a self-driving aortic-turbine venous-assist device for Fontan patients

K Pekkan, IB Aka, E Tutsak, E Ermek, H Balim… - The Journal of thoracic …, 2018 - Elsevier
Background Palliative repair of single ventricle defects involve a series of open-heart
surgeries where a single-ventricle (Fontan) circulation is established. As the patient ages …

[HTML][HTML] A pulsatile hemodynamic evaluation of the commercially available bifurcated Y-graft Fontan modification and comparison with the lateral tunnel and …

PM Trusty, M Restrepo, KR Kanter… - The Journal of Thoracic …, 2016 - Elsevier
Objective Fontan completion, resulting in a total cavopulmonary connection, is
accomplished using a lateral tunnel, extracardiac conduit, or bifurcated Y-graft. The use of Y …

Mock circulatory system of the Fontan circulation to study respiration effects on venous flow behavior

M Vukicevic, JA Chiulli, T Conover, G Pennati… - ASAIO …, 2013 - journals.lww.com
We describe an in vitro model of the Fontan circulation with respiration to study
subdiaphragmatic venous flow behavior. The venous and arterial connections of a total …