Oocyte maturation arrest, fertilization failure, and early embryonic arrest are important
causes of female infertility, whereas the genetic events that contribute to these processes …

Preimplantation embryonic arrest is an important pathogenesis of female infertility, but little
is known about the genetic factors behind this phenotype. MEI4 is an essential protein for …

正常的卵子发生是人类成功繁育后代的关键步骤. 女性胚胎发育时期, 原始生殖细胞从有丝分裂
转变为减数分裂, 经过同源染色体配对和重组后, 减数分裂被阻滞在减数第一次分裂前期的双线 …

Assisted reproduction procedures often encounter an issue called oocyte maturation arrest
(OMA), which is manifested as failed IVF/ICSI attempts using oocytes from some infertile …

Women undergoing controlled ovarian hyperstimulation prior to in vitro fertilization (IVF) are
treated using various protocols to induce multiple follicular growths. Complete failure of all …

Purpose To explore the pathogenesis of oocyte maturation defects. Methods Whole exome
sequencing was conducted to identify potential variants, which were then confirmed within …