As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …

The blood-brain barrier (BBB) is a dynamic, highly selective barrier primarily formed by
endothelial cells connected by tight junctions that separate the circulating blood from the …

MRI-guided pulsed focused ultrasound (pFUS) combined with systemic infusion of
ultrasound contrast agent microbubbles (MB) causes localized blood–brain barrier (BBB) …

In recent years there has been a resurgence of interest in brain barriers and various roles
their intrinsic mechanisms may play in neurological disorders. Such studies require suitable …

Our understanding of BBB breakdown acutely after the cerebrovascular injury has come a
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …

Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …

Focused Ultrasound (FUS) in combination with gaseous microbubbles has emerged as a
potential new means of effective drug delivery to the brain. Recent research has shown that …

Spreading depolarization (SD) is a phenomenon of various cerebral gray matter structures
that only occurs under pathological conditions. In the present paper, we summarize the …

Sodium butyrate (NaB) has exhibited protective activity in neurological disorders. Here, we
investigated the neuroprotective effect and potential mechanisms of NaB in a mouse model …

Claudin-5 is a tight junction (TJ) protein in the blood-brain barrier (BBB) that has recently
attracted increased attention. Numerous studies have demonstrated that claudin-5 regulates …