Extracellular vesicles in kidney disease

C Grange, B Bussolati - Nature Reviews Nephrology, 2022 - nature.com
Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …

Exosomes: roles and therapeutic potential in osteoarthritis

Z Ni, S Zhou, S Li, L Kuang, H Chen, X Luo, J Ouyang… - Bone research, 2020 - nature.com
Exosomes participate in many physiological and pathological processes by regulating cell–
cell communication, which are involved in numerous diseases, including osteoarthritis (OA) …

Targeted therapy for inflammatory diseases with mesenchymal stem cells and their derived exosomes: from basic to clinics

S Wang, B Lei, E Zhang, P Gong, J Gu… - International Journal …, 2022 - Taylor & Francis
Inflammation is a beneficial and physiological process, but there are a number of
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …

Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis

S Zhao, G Xiu, J Wang, Y Wen, J Lu, B Wu… - Journal of …, 2023 - Springer
Osteoarthritis (OA) is a degenerative joint disease involving cartilage. Exosomes derived
from Mesenchymal stem cells (MSCs) therapy improves articular cartilage repair, but …

Comparing the therapeutic potential of stem cells and their secretory products in regenerative medicine

JB Foo, QH Looi, PP Chong, NH Hassan… - Stem cells …, 2021 - Wiley Online Library
Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

MicroRNA-377-3p released by mesenchymal stem cell exosomes ameliorates lipopolysaccharide-induced acute lung injury by targeting RPTOR to induce autophagy

X Wei, X Yi, H Lv, X Sui, P Lu, L Li, Y An, Y Yang… - Cell death & …, 2020 - nature.com
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the severe lung
damage and respiratory failure without effective therapy. However, there was a lack of …

[HTML][HTML] Mesenchymal stromal cell-derived exosomes in cardiac regeneration and repair

SJ Sun, R Wei, F Li, SY Liao, HF Tse - Stem cell reports, 2021 - cell.com
Mesenchymal stromal cell (MSC)-derived exosomes play a promising role in regenerative
medicine. Their trophic and immunomodulatory potential has made them a promising …

Roles for exosome in various kidney diseases and disorders

V Thongboonkerd - Frontiers in pharmacology, 2020 - frontiersin.org
Exosome is a nanoscale vesicle with a size range of 30–100 nm. It is secreted from cell to
extracellular space by exocytosis after fusion of multivesicular body (MVB)(formed by …

Extracellular vesicles derived from different sources of mesenchymal stem cells: therapeutic effects and translational potential

J Cai, J Wu, J Wang, Y Li, X Hu, S Luo, D Xiang - Cell & bioscience, 2020 - Springer
Mesenchymal stem cells (MSCs) were known to have excellent properties in cell therapy.
However, the risk of immune rejection associated with cell transplant therapy hampers its …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine

ZJ Ma, JJ Yang, YB Lu, ZY Liu… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are multipotent stem cells with marked potential for
regenerative medicine because of their strong immunosuppressive and regenerative …