Current understanding of immune thrombocytopenia: a review of pathogenesis and treatment options
A Mititelu, MC Onisâi, A Roșca… - International Journal of …, 2024 - mdpi.com
The management of immune thrombocytopenia (ITP) and the prediction of patient response
to therapy still represent a significant and constant challenge in hematology. ITP is a …
to therapy still represent a significant and constant challenge in hematology. ITP is a …
IL-22, a vital cytokine in autoimmune diseases
J Li, Z Wu, Y Wu, XY Hu, J Yang, D Zhu… - Clinical and …, 2024 - academic.oup.com
Summary Interleukin-22 (IL-22) is a vital cytokine that is dysregulated in various autoimmune
conditions including rheumatoid arthritis (RA), multiple sclerosis (MS), and Alzheimer's …
conditions including rheumatoid arthritis (RA), multiple sclerosis (MS), and Alzheimer's …
[PDF][PDF] 皮质激素耐药或依赖的成人免疫性血小板减少症的治疗
彭军 - 临床血液学杂志, 2024 - lcxyen.whuhzzs.com
免疫性血小板减少症(immunethrombocytopenia, ITP) 是一种常见的自身免疫性出血性疾病,
表现为外周血血小板计数减低. 针对ITP 的经典初始治疗方案仍为糖皮质激素 …
表现为外周血血小板计数减低. 针对ITP 的经典初始治疗方案仍为糖皮质激素 …
Efficacy and safety of sovleplenib (HMPL-523) in adult patients with chronic primary immune thrombocytopenia in China (ESLIM-01): a randomised, double-blind …
Y Hu, X Liu, H Zhou, S Wang, R Huang… - The Lancet …, 2024 - thelancet.com
Background Sovleplenib, a novel spleen tyrosine kinase (SYK) inhibitor, showed promising
safety and activity in patients with primary immune thrombocytopenia in a phase 1b/2 trial …
safety and activity in patients with primary immune thrombocytopenia in a phase 1b/2 trial …
Meddiffusion: Boosting health risk prediction via diffusion-based data augmentation
Health risk prediction aims to forecast the potential health risks that patients may face using
their historical Electronic Health Records (EHR). Although several effective models have …
their historical Electronic Health Records (EHR). Although several effective models have …
Causal relationship between gut microbiota and immune thrombocytopenia: a Mendelian randomization study of two samples
D Guo, Q Chen, G Wang, CP Li… - Frontiers in …, 2023 - frontiersin.org
Background Some observational studies have shown that immune thrombocytopenia (ITP)
is highly associated with the alteration-composition of gut microbiota. However, the causality …
is highly associated with the alteration-composition of gut microbiota. However, the causality …
Proteomics landscape and machine learning prediction of long‐term response to splenectomy in primary immune thrombocytopenia
T Sun, J Chen, Y Xu, Y Li, X Liu, H Li… - British Journal of …, 2024 - Wiley Online Library
This study aimed to identify key proteomic analytes correlated with response to splenectomy
in primary immune thrombocytopenia (ITP). Thirty‐four patients were retrospectively …
in primary immune thrombocytopenia (ITP). Thirty‐four patients were retrospectively …
Identification of metabolism-related key genes as potential biomarkers for pathogenesis of immune thrombocytopenia
X Xu, J Zhang, H Xing, L Han, X Li, P Wu, J Tang… - Scientific Reports, 2024 - nature.com
Immune thrombocytopenia (ITP), an acquired autoimmune disease, is characterized by
immune-mediated platelet destruction. A biomarker is a biological entity that contributes to …
immune-mediated platelet destruction. A biomarker is a biological entity that contributes to …
[HTML][HTML] Recent advances in the management of immune thrombocytopenic purpura (ITP): A comprehensive review
MA Madkhali - Medicine, 2024 - journals.lww.com
Autoimmune disorders place a substantial burden on the healthcare system all over the
world affecting almost 3% to 8% of the population. Immune thrombocytopenic purpura (ITP) …
world affecting almost 3% to 8% of the population. Immune thrombocytopenic purpura (ITP) …
Translating mechanisms into therapeutic strategies for immune thrombocytopenia (ITP): Lessons from clinical trials
M Delshad, Z Davoodi-Moghaddam… - Thrombosis …, 2024 - Elsevier
Immune thrombocytopenia (ITP) is an autoimmune disorder that causes a significant
reduction in peripheral blood platelet count. Fortunately, due to an increased understanding …
reduction in peripheral blood platelet count. Fortunately, due to an increased understanding …