Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

Acetylation is a posttranslational modification conserved in all domains of life that is carried
out by N-acetyltransferases. While acetylation can occur on N α-amino groups, this review …

The EcoCyc model-organism database collects and summarizes experimental data for
Escherichia coli K-12. EcoCyc is regularly updated by the manual curation of individual …

Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …

Protein acetylation is a highly frequent protein modification. However, comparatively little is
known about its enzymatic machinery. N‐α‐acetylation (NTA) and ε‐lysine acetylation (KA) …

As critical executors regulating many cellular operations, proteins determine whether living
activities can be performed in an orderly and efficient manner. Precursor proteins are inert …

Over the past decades, our understanding of microbial metabolism has increased
dramatically. Metabolomics, a family of techniques that are used to measure the quantities of …

Protein-modifying enzymes regulate the dynamics of myriad post-translational modification
(PTM) substrates. Precise characterization of enzyme-substrate associations is essential for …

SARS-CoV-2 non-structural protein Nsp14 is a highly conserved enzyme necessary for viral
replication. Nsp14 forms a stable complex with non-structural protein Nsp10 and exhibits …

The chemical modification of ribosomes plays an important regulatory role in cellular
translation adaptation in response to environmental stresses. Nevertheless, how the …