Tailoring biomaterials for cancer immunotherapy: emerging trends and future outlook

C Wang, Y Ye, Q Hu, A Bellotti, Z Gu - Advanced materials, 2017 - Wiley Online Library
Cancer immunotherapy, as a paradigm shift in cancer treatment, has recently received
tremendous attention. The active cancer vaccination, immune checkpoint blockage (ICB) …

Advances in immunotherapy delivery from implantable and injectable biomaterials

DG Leach, S Young, JD Hartgerink - Acta biomaterialia, 2019 - Elsevier
Macroscale biomaterials, such as preformed implantable scaffolds and injectable soft
materials, possess powerful synergies with anti-cancer immunotherapies. Immunotherapies …

Improving vaccine and immunotherapy design using biomaterials

ML Bookstaver, SJ Tsai, JS Bromberg, CM Jewell - Trends in immunology, 2018 - cell.com
Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as
technologies to improve the efficacy of vaccines against infectious disease and …

Designing biomaterials with immunomodulatory properties for tissue engineering and regenerative medicine

JI Andorko, CM Jewell - Bioengineering & translational …, 2017 - Wiley Online Library
Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …

Designing inorganic nanomaterials for vaccines and immunotherapies

KL Hess, IL Medintz, CM Jewell - Nano Today, 2019 - Elsevier
Vaccines and immunotherapies have changed the face of health care. Biomaterials offer the
ability to improve upon these medical technologies through increased control of the types …

Polysaccharide-based nanocomposites for biomedical applications: a critical review

H Shokrani, A Shokrani, SM Sajadi, MK Yazdi… - Nanoscale …, 2022 - pubs.rsc.org
Polysaccharides (PSA) have taken specific position among biomaterials for advanced
applications in medicine. Nevertheless, poor mechanical properties are known as the main …

Phage display as a tool for vaccine and immunotherapy development

KL Hess, CM Jewell - Bioengineering & translational medicine, 2020 - Wiley Online Library
Bacteriophages, or phages, are viruses that specifically infect bacteria and coopt the cellular
machinery to create more phage proteins, eventually resulting in the release of new phage …

Facile fabrication of tumor redox‐sensitive nanoassemblies of small‐molecule oleate prodrug as potent chemotherapeutic nanomedicine

C Luo, J Sun, B Sun, D Liu, L Miao, TJ Goodwin… - Small, 2016 - Wiley Online Library
The conjugate of paclitaxel (PTX) and docosahexaenoic acid has entered into clinical trials.
However, the most recent clinical outcomes fell short of expectations, due to the extremely …

Phage engineering and phage‐assisted CRISPR‐Cas delivery to combat multidrug‐resistant pathogens

K Khambhati, G Bhattacharjee, N Gohil… - Bioengineering & …, 2023 - Wiley Online Library
Antibiotic resistance ranks among the top threats to humanity. Due to the frequent use of
antibiotics, society is facing a high prevalence of multidrug resistant pathogens, which have …

[HTML][HTML] Biomaterial-based delivery platforms for transdermal immunotherapy

M Dahri, N Beheshtizadeh, N Seyedpour… - Biomedicine & …, 2023 - Elsevier
Nowadays, immunotherapy is one of the most essential treatments for various diseases and
a broad spectrum of disorders are assumed to be treated by altering the function of the …