Historically, positron emission tomography (PET) systems have been based on scintillation
crystals coupled to photomultipliers tubes (PMTs). However, the limited quantum efficiency …

PET scanners are sophisticated and highly sensitive biomedical imaging devices that can
produce highly quantitative images showing the 3-dimensional distribution of radiotracers …

Machine learning has found unique applications in nuclear medicine from photon detection
to quantitative image reconstruction. Although there have been impressive strides in …

Silicon photomultipliers (SiPMs) are of great interest to positron emission tomography (PET),
as they enable new detector geometries, for eg, depth-of-interaction (DOI) determination, are …

Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

A new preclinical PET system based on dSiPMs, called DigiPET, is presented. The system is
based on thin monolithic scintillation crystals and exhibits superior spatial resolution at low …

When principal component analysis (PCA) is used for statistical process monitoring it relies
on the assumption that data are time independent. However, industrial data will often exhibit …

Monolithic scintillator detectors can offer a combination of spatial resolution, energy
resolution, timing performance, depth-of-interaction information, and detection efficiency that …

In this article, we describe recent developments in the design of both single-photon emission
computed tomography (SPECT) and positron emission tomography (PET) instrumentation …

Positron emission tomography (PET) is used in the clinic and in vivo small animal research
to study molecular processes associated with diseases such as cancer, heart disease, and …