Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

Interleukins, a group of cytokines participating in inflammation and immune response, are
proved to be involved in the formation and development of pulmonary fibrosis. In this article …

The gut microbiota has been implicated in chronic pain disorders, including irritable bowel
syndrome (IBS), yet specific pathophysiological mechanisms remain unclear. We showed …

Immune responses are governed by signals from the tissue microenvironment, and in
addition to biochemical signals, mechanical cues and forces arising from the tissue, its …

It is well known that mast cells (MCs) initiate type I allergic reactions and inflammation in a
quick response to the various stimulants, including—but not limited to—allergens, pathogen …

Patients with idiopathic pulmonary fibrosis (IPF) have a high risk of developing lung cancer
compared with the general population. The morbidity of lung cancer in IPF patient ranges …

Mast cells are widely distributed in various parts of the human body and play a vital role in
the progression of many diseases. Recently, the close relationship between mast cells and …

Pulmonary fibrosis arises from the repeated epithelial mild injuries and insufficient repair
lead to over activation of fibroblasts and excessive deposition of extracellular matrix, which …

Idiopathic pulmonary fibrosis (IPF) is a long-lasting, continuously advancing, and irrevocable
interstitial lung disorder with an obscure origin and inadequately comprehended …

Background: Chronic pulmonary diseases are characterized by airway remodeling due to
complex multicellular responses and the production of free oxygen radicals. They lead to a …