Chronic subdural hematoma (CSH) affects mostly elderly subjects. Previously,
pathophysiological concepts suggested that CSH is secondary to degradation of subdural …

Background GRP78 has been implicated in hepatocarcinogenesis. However, the clinical
relevance, biological functions and related regulatory mechanisms of GRP78 in hepatitis B …

Flavonoids, stilbenes, and chalcones are plant secondary metabolites that often possess
diverse biological activities including anti-inflammatory, anti-cancer, and anti-viral activities …

Abstract DEAD (Asp-Glu-Ala-Asp) box helicase 5 (DDX5) is an ATP-dependent RNA
helicase that is overexpressed in various malignancies. Increasing evidence suggests that …

The high mobility group AT-Hook (HMGA) proteins are a family of nonhistone chromatin
remodeling proteins known as “architectural transcriptional factors”. By binding the minor …

It has been proven that long non‑coding (lnc) RNAs serve an important role in the
tumorigenesis and development of several types of human malignancy. Previous studies …

Chondrosarcoma is a malignancy of soft tissue and bone that has a high propensity to
metastasize to distant organs. Nerve growth factor (NGF) is critical for neuronal cell growth …

While Bufalin restrains primary tumorigenesis, the role of Bufalin in cervical cancer remains
unclear. Here, we show that Bufalin can inhibit cervical cancer cell proliferation, block cell …

Ursolic acid (UA), is a kind of triterpene acid that exhibits wide biological properties. In this
article, the effects of UA on apoptosis and the proliferation of human hepatoma Huh-7 cells …

SUMMARY OBJECTIVE: The phosphoinositide 3-kinase/protein kinase AKT/mammalian
target of rapamycin signaling pathway is essential for proper cellular metabolism and cell …