[HTML][HTML] Targeted therapies for pediatric AML: gaps and perspective
Acute myeloid leukemia (AML) is a hematopoietic disorder characterized by numerous
cytogenetic and molecular aberrations that accounts for~ 25% of childhood leukemia …
cytogenetic and molecular aberrations that accounts for~ 25% of childhood leukemia …
Pediatric acute myeloid leukemia: Insight into genetic landscape and novel targeted approaches
Acute myeloid leukemia (AML) is a very heterogeneous hematological malignancy that
accounts for approximately 20% of all pediatric leukemia cases. The outcome of pediatric …
accounts for approximately 20% of all pediatric leukemia cases. The outcome of pediatric …
[HTML][HTML] Occurrence of treatment-related cardiotoxicity and its impact on outcomes among children treated in the AAML0531 clinical trial: a report from the Children's …
Purpose Late cardiotoxicity after pediatric acute myeloid leukemia therapy causes
substantial morbidity and mortality. The impact of early-onset cardiotoxicity on treatment …
substantial morbidity and mortality. The impact of early-onset cardiotoxicity on treatment …
[HTML][HTML] Effect of dexrazoxane on left ventricular systolic function and treatment outcomes in patients with acute myeloid leukemia: a report from the Children's …
Effect of Dexrazoxane on Left Ventricular Systolic Function and Treatment Outcomes in Patients
With Acute Myeloid Leukemia: A Report From the Children’s Oncology Group - PMC Back to …
With Acute Myeloid Leukemia: A Report From the Children’s Oncology Group - PMC Back to …
Prognostic impact of t (16; 21)(p11; q22) and t (16; 21)(q24; q22) in pediatric AML: a retrospective study by the I-BFM Study Group
S Noort, M Zimmermann, D Reinhardt… - Blood, The Journal …, 2018 - ashpublications.org
To study the prognostic relevance of rare genetic aberrations in acute myeloid leukemia
(AML), such as t (16; 21), international collaboration is required. Two different types of t (16; …
(AML), such as t (16; 21), international collaboration is required. Two different types of t (16; …
[HTML][HTML] Analysis of rare driving events in pediatric acute myeloid leukemia
S Noort, J van Oosterwijk, J Ma, EAR Garfinkle… - …, 2023 - ncbi.nlm.nih.gov
Elucidating genetic aberrations in pediatric acute myeloid leukemia (AML) provides insight
in biology and may impact on risk-group stratification and clinical outcome. This study aimed …
in biology and may impact on risk-group stratification and clinical outcome. This study aimed …
Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML
Etoposide is used to treat a wide range of malignant cancers, including acute myeloid
leukemia (AML) in children. Despite the use of intensive chemotherapeutic regimens …
leukemia (AML) in children. Despite the use of intensive chemotherapeutic regimens …
Long non-coding RNA UCA1 modulates cell proliferation and apoptosis by regulating miR-296-3p/Myc axis in acute myeloid leukemia
J Li, M Wang, X Chen - Cell cycle, 2020 - Taylor & Francis
Acute myeloid leukemia (AML) is a common hematopoietic malignancy with a generally
poor prognosis. Long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) …
poor prognosis. Long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) …
Outcome of pediatric acute myeloid leukemia (AML) in low-and middle-income countries: a systematic review of the literature
RE Van Weelderen, K Klein… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Survival rates of pediatric acute myeloid leukemia (AML) in low-and middle-
income countries (LMICs) seem extremely poor, and the available literature on the matter is …
income countries (LMICs) seem extremely poor, and the available literature on the matter is …
[HTML][HTML] The role of forkhead box proteins in acute myeloid leukemia
C Gurnari, G Falconi, E De Bellis, MT Voso, E Fabiani - Cancers, 2019 - mdpi.com
Forkhead box (FOX) proteins are a group of transcriptional factors implicated in different
cellular functions such as differentiation, proliferation and senescence. A growing number of …
cellular functions such as differentiation, proliferation and senescence. A growing number of …