[HTML][HTML] Single-photon avalanche diode imagers in biophotonics: review and outlook

C Bruschini, H Homulle, IM Antolovic, S Burri… - Light: Science & …, 2019 - nature.com
Single-photon avalanche diode (SPAD) arrays are solid-state detectors that offer imaging
capabilities at the level of individual photons, with unparalleled photon counting and time …

[HTML][HTML] Time-gated single-photon detection in time-domain diffuse optics: a review

A Dalla Mora, L Di Sieno, R Re, A Pifferi, D Contini - Applied Sciences, 2020 - mdpi.com
This work reviews physical concepts, technologies and applications of time-domain diffuse
optics based on time-gated single-photon detection. This particular photon detection …

[HTML][HTML] Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise

P Lanka, L Yang, D Orive-Miguel… - Journal of …, 2022 - spiedigitallibrary.org
Significance: Multi-laboratory initiatives are essential in performance assessment and
standardization—crucial for bringing biophotonics to mature clinical use—to establish …

Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy

S Mosca, P Lanka, N Stone… - Biomedical optics …, 2020 - opg.optica.org
We present a systematic characterization of the optical properties (µ_a and µ_s') of nine
representative ex vivo porcine tissues over a broadband spectrum (650-1100 nm). We …

The SiPM revolution in time-domain diffuse optics

A Dalla Mora, L Di Sieno, A Behera, P Taroni… - Nuclear Instruments and …, 2020 - Elsevier
Time-domain diffuse optics is a powerful non-invasive, non-ionizing and label-free
technique based on the use of picosecond pulsed laser light to probe highly scattering …

Spatially offset and transmission Raman spectroscopy for determination of depth of inclusion in turbid matrix

S Mosca, P Dey, TA Tabish, F Palombo… - Analytical …, 2019 - ACS Publications
We propose an approach for the prediction of the depth of a single buried object within a
turbid medium combining spatially offset Raman spectroscopy (SORS) and transmission …

0.5 billion counts per second enable high speed and penetration in time-domain diffuse optics

L Di Sieno, T Talala, E Avanzi, I Nissinen… - IEEE Journal of …, 2023 - ieeexplore.ieee.org
We present the application to time-domain diffuse optics of a high-speed 8× 256 array of
single-photon avalanche diodes with integrated 256 parallel time-to-digital converters …

Probe-hosted large area silicon photomultiplier and high-throughput timing electronics for enhanced performance time-domain functional near-infrared spectroscopy

L Di Sieno, A Behera, S Rohilla, E Ferocino… - Biomedical Optics …, 2020 - opg.optica.org
Two main bottlenecks prevent time-domain diffuse optics instruments to reach their
maximum performances, namely the limited light harvesting capability of the detection chain …

[HTML][HTML] In vivo optimization of the experimental conditions for the non-invasive optical assessment of breast density

N Serra, R Cubeddu, G Maffeis, V Damagatla… - Scientific Reports, 2024 - nature.com
In this study, time domain diffuse optical spectroscopy is performed in the range 600–1100
nm on 11 healthy volunteers with a portable system for the quantitative characterization of …

Wearable SiPM-based NIRS interface integrated with pulsed laser source

S Saha, Y Lu, F Lesage… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
We present the design of a miniaturized probe integrating silicon photomultiplier and light-
pulsing electronics in a single 2× 2 mm 2 complementary metal-oxide-semiconductor …