Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update

S Abraham Gnanadass, Y Divakar Prabhu… - Archives of Gynecology …, 2021 - Springer
Background Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder
in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian …

[HTML][HTML] The role of innate and adaptive immune cells in the pathogenesis and development of the inflammatory response in ulcerative colitis

A Kałużna, P Olczyk, K Komosińska-Vassev - Journal of clinical medicine, 2022 - mdpi.com
Ulcerative colitis (UC) is a chronic inflammatory disease with an underlying excessive
immune response directed against resident microbiota and/or dietary antigens. Both innate …

[HTML][HTML] Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

A Alam, E Levanduski, P Denz, HS Villavicencio… - Cancer cell, 2022 - cell.com
TH 2 cells and innate lymphoid cells 2 (ILC2) can stimulate tumor growth by secreting pro-
tumorigenic cytokines such as interleukin-4 (IL-4), IL-5, and IL-13. However, the …

Cytokine‐and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy

AA Bhat, S Nisar, M Singh, B Ashraf… - Cancer …, 2022 - Wiley Online Library
Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …

Fullerenes in biology and medicine

E Castro, AH Garcia, G Zavala… - Journal of Materials …, 2017 - pubs.rsc.org
Fullerenes and related carbon based derivatives have shown a growing relevance in
biology and medicine, mainly due to the unique electronic and structural properties that …

A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

M Salimi, JL Barlow, SP Saunders, L Xue… - Journal of Experimental …, 2013 - rupress.org
Type 2 innate lymphoid cells (ILC2s, nuocytes, NHC) require RORA and GATA3 for their
development. We show that human ILC2s express skin homing receptors and infiltrate the …

[HTML][HTML] IL-1 family members mediate cell death, inflammation and angiogenesis in retinal degenerative diseases

Y Wooff, SM Man, R Aggio-Bruce, R Natoli… - Frontiers in …, 2019 - frontiersin.org
Inflammation underpins and contributes to the pathogenesis of many retinal degenerative
diseases. The recruitment and activation of both resident microglia and recruited …

IL-25 (IL-17E) in epithelial immunology and pathophysiology

J Borowczyk, M Shutova, NC Brembilla… - Journal of Allergy and …, 2021 - Elsevier
IL-25, also known as IL-17E, is a unique cytokine of the IL-17 family. Indeed, IL-25
exclusively was shown to strongly induce expression of the cytokines associated with type 2 …

Activated T lymphocytes are essential drivers of pathological remodeling in ischemic heart failure

SS Bansal, MA Ismahil, M Goel, B Patel… - Circulation: Heart …, 2017 - Am Heart Assoc
Background—Inappropriately sustained inflammation is a hallmark of chronic ischemic heart
failure (HF); however, the pathophysiological role of T lymphocytes is unclear. Methods and …

[HTML][HTML] New cytokines in the pathogenesis of atopic dermatitis—new therapeutic targets

J Klonowska, J Gleń, RJ Nowicki… - International journal of …, 2018 - mdpi.com
Atopic dermatitis (AD) is a recurrent, chronic, and inflammatory skin disease, which
processes with severe itchiness. It often coexists with different atopic diseases. The number …