Inflammation and lymphatic function
S Schwager, M Detmar - Frontiers in immunology, 2019 - frontiersin.org
The lymphatic vasculature plays a crucial role in regulating the inflammatory response by
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …
The emerging importance of lymphatics in health and disease: an NIH workshop report
The lymphatic system (LS) is composed of lymphoid organs and a network of vessels that
transport interstitial fluid, antigens, lipids, cholesterol, immune cells, and other materials in …
transport interstitial fluid, antigens, lipids, cholesterol, immune cells, and other materials in …
Acid-activatable polymeric curcumin nanoparticles as therapeutic agents for osteoarthritis
Curcumin, a primary active element of turmeric, has potent antioxidant and anti-inflammatory
activity, but its low bioavailability is a major hurdle in its pharmaceutical applications. To …
activity, but its low bioavailability is a major hurdle in its pharmaceutical applications. To …
B cells in rheumatoid arthritis: from pathogenic players to disease biomarkers
S Bugatti, B Vitolo, R Caporali… - BioMed research …, 2014 - Wiley Online Library
The therapeutic benefit of depleting B cells in rheumatoid arthritis (RA) has refocused
attention on B cells with increasing awareness on their role in autoimmunity and their …
attention on B cells with increasing awareness on their role in autoimmunity and their …
Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis
Although clinical outcomes for patients with rheumatoid arthritis (RA) have greatly improved
with the use of biologic and conventional DMARDs, approximately 40% of patients do not …
with the use of biologic and conventional DMARDs, approximately 40% of patients do not …
Lymphangiogenesis and cancer metastasis
V Mumprecht, M Detmar - Journal of cellular and molecular …, 2009 - Wiley Online Library
Anatomy and function of the lymphatic system• Tumour‐induced lymphangiogenesis
promotes metastasis• Tumour‐induced lymph node lymphangiogenesis precedes cancer …
promotes metastasis• Tumour‐induced lymph node lymphangiogenesis precedes cancer …
Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse …
Objective This study was undertaken to investigate the effect of lymphatic inhibition on joint
and draining lymph node (LN) pathology during the course of arthritis progression in mice …
and draining lymph node (LN) pathology during the course of arthritis progression in mice …
Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice
Objective To investigate whether the enhancement of joint lymphangiogenesis by injection
of vascular endothelial growth factor C (VEGF‐C) adeno‐associated virus (AAV) into the …
of vascular endothelial growth factor C (VEGF‐C) adeno‐associated virus (AAV) into the …
[HTML][HTML] Lymphatic vessels: Roles and potential therapeutic intervention in rheumatoid arthritis and osteoarthritis
S Zhou, G Zhao, R Chen, Y Li, J Huang, L Kuang… - Theranostics, 2024 - ncbi.nlm.nih.gov
Lymphatic vessel networks are a main part of the vertebrate cardiovascular system, which
participate in various physiological and pathological processes via regulation of fluid …
participate in various physiological and pathological processes via regulation of fluid …
Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells
Abstract Cytotoxic T-Lymphocytes (CTLs) kill pathogen-infected or transformed cells
following interaction of their T-cell receptors (TCRs) with foreign (eg virus-derived) peptides …
following interaction of their T-cell receptors (TCRs) with foreign (eg virus-derived) peptides …